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The wet macular degeneration market attained a value of USD 9.53 Billion in 2024, driven by the rising aging population and advancements in treatment options across the 8 major markets. It is expected to grow at a CAGR of 5.90% in the forecast period of 2025-2034, and attain a value of USD 16.91 Billion by 2034.
Base Year
Historical Year
Forecast Year
Progress in anti-VEGF treatments, such as ranibizumab and aflibercept, alongside developments like gene therapies and long-acting treatments, are increasing treatment choices and driving market growth.
In September 2024, the FDA approved Pavblu as the fifth biosimilar referencing Eylea. The acceptance of numerous biosimilars enhances competition, leading to market expansion by enhancing accessibility and affordability of treatment.
The United States is expected to dominate the market, driven by its sophisticated healthcare system, large aging population, and significant investment in research and advanced treatment options.
Value in USD Billion
2025-2034
Wet Macular Degeneration Market Outlook
*this image is indicative*
Wet macular degeneration (or neovascular AMD) is a long-term disease that affects central vision in senior citizens. Wet macular degeneration is a more serious condition and is a type of AMD marked by a severe, rapid loss of central vision in the retina where macular degeneration has occurred. This condition develops when the small blood vessels beneath the macula of the retina swarm and ooze out fluids like blood. While the rest of the retina is involved in the peripheral vision, the macula is responsible for the central vision, necessary for reading or identifying faces. Symptoms are effectively controlled by early intervention, and medications like anti-VEGF injections can delay the progression of the condition.
Increasing Aging Population to Boost the Market Growth
In a report, the World Health Organization (WHO) highlighted that with increasing life expectancy, a large number of individuals will reach 60 or older by 2050. Wet macular degeneration cases are bound to surge with the increasing incidence of the geriatric population base, leading to increased demand for treatment among the elderly with vision-related diseases.
FDA Approval Boosts the Market Growth
In September 2024, Pavblu, the fifth biosimilar referencing Eylea (aflibercept), was approved by the FDA for the treatment of retinal conditions such as wet age-related macular degeneration. Pavblu, developed by Amgen, was approved after a phase 3 study with 576 patients from various countries. It is one of several biosimilars that got approval in 2024, along with Yesafili, Opuviz, Ahzantive, and Enzeevu. There is a growing emphasis on early detection and preventive healthcare. Increasing approvals from essential regulatory authorities is expected to boost the market value in the forecast period.
The market is witnessing several trends and developments to improve the current scenario. Some of the notable trends are as follows:
The report offers a detailed analysis of the market based on the following segments:
Market Breakup by Disease Stage:
Market Breakup by Treatment Type:
Market Breakup by Route of Administration:
Market Breakup by End User:
Market Breakup by Region:
Market Segmentation Based on the Route of Administration Set to Witness Substantial Growth
The market is segmented into intravenous route and intravitreal route based on the route of administration. Among these, the intravitreal method is expected to dominate the market because it directly administers drugs into the eye, resulting in improved treatment results and fewer overall side effects. Medications such as Ranibizumab (Lucentis) and Aflibercept (Eylea) are often given through injections directly into the eye. This technique enables focused treatment of the retina, effectively preventing the growth of abnormal blood vessels. Due to its established efficacy and lower risks when compared to systemic delivery, intravitreal therapy continues to be considered the preferred treatment method for wet AMD.
Segmentation Based on End User Holds a Significant Market Share
The market is divided into hospitals, clinics, ambulatory surgical centers, homecare settings, and others. Among these, hospitals and clinics are expected to dominate the market because of their specialized ophthalmologists and advanced diagnostic equipment. They provide thorough treatment, which includes giving anti-VEGF medications such as Lucentis and Eylea via injections into the eye. Ambulatory surgical centers also hold a substantial share due to their affordability, while homecare settings are utilized for remote monitoring and occasional medical care.
Based on region, the market report covers the United States, EU-4, and the United Kingdom (Germany, France, Italy, Spain, United Kingdom), Japan, and India. Due to advanced healthcare systems and substantial investment in research, the United States is expected to dominate the market. Factors like increasing elderly populations and lifestyle-related risks impact the market in this area. The government's backing promotes market expansion through leadership in clinical trials and innovative treatments such as targeted therapies and immunotherapies. The market is growing due to greater emphasis on early detection and personalized treatment choices.
The key features of the market report include patent analysis, clinical trials analysis, grants analysis, funding and investment analysis, and strategic initiatives by the leading players. The major companies are:
Bayer AG, headquartered in Leverkusen, Germany, is a leading pharmaceutical company in the age-related wet macular degeneration (AMD) market. Their primary product, Eylea (aflibercept), is a very effective treatment for wet AMD that can preserve and even improve vision. Bayer remains committed to investing in the research and development of new AMD therapies.
Established in 1896 and headquartered in Basel, Switzerland. Roche specializes in ophthalmic disorder drugs. They developed Lucentis, a popular anti-VEGF therapy drug for wet AMD, through Genentech. They are working on new delivery methods and long-acting formulations to reduce reliance on frequent injections in AMD treatment, leveraging their biopharmaceutical expertise.
Pfizer Inc. is a significant player in the wet age-related macular degeneration (AMD) market, which is highly competitive and poised for growth due to the aging global population and the rising prevalence of eye disorders.
Novartis AG is a leading player in the market, primarily through its flagship drug, Lucentis (ranibizumab), a pioneering anti-VEGF therapy developed in partnership with Genentech.
*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*
Other companies include Panoptica Pharma, Bausch + Lomb, Regeneron Pharmaceuticals Inc., Ocugen Inc., REGENXBIO Inc., and Oxurion NV, among others.
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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REPORT FEATURES | DETAILS |
Base Year | 2024 |
Historical Period | 2018-2024 |
Forecast Period | 2025-2034 |
Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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Breakup by Disease Stage |
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Breakup by Treatment Type |
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Breakup by Route of Administration |
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Breakup by End User |
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Breakup by Region |
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Market Dynamics |
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Supplier Landscape |
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Companies Covered |
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United States (Head Office)
30 North Gould Street, Sheridan, WY 82801
+1-415-325-5166
Australia
63 Fiona Drive, Tamworth, NSW
+61-448-061-727
India
C130 Sector 2 Noida, Uttar Pradesh 201301
+91-723-689-1189
Philippines
40th Floor, PBCom Tower, 6795 Ayala Avenue Cor V.A Rufino St. Makati City, 1226.
+63-287-899-028, +63-967-048-3306
United Kingdom
6 Gardner Place, Becketts Close, Feltham TW14 0BX, Greater London
+44-753-713-2163
Vietnam
193/26/4 St.no.6, Ward Binh Hung Hoa, Binh Tan District, Ho Chi Minh City
+84-865-399-124
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