Report Overview

The vaso occlusive crisis market was valued at USD 4.19 Billion in 2023, driven by the increasing prevalence of sickle cell disease across the 8 major markets. The market is expected to grow at a CAGR of 14.74% during the forecast period of 2024-2032, with the values likely to reach USD 14.44 Billion by 2032.

2023

Base Year

2017-2023

Historical Year

2024-2032

Forecast Year

  • Since vaso occlusive crisis is one of the most common clinical manifestations of sickle cell anemia, the rising disease burden is expected to fuel the market demand in the forecast period.
  • In December 2023, two cell-based gene therapies Casgevy and Lyfgenia were approved by the U.S. Food and Drug Administration for the treatment of sickle cell disease. The rise in such innovative drug approvals by the health authorities is a major market trend.
  • The increase in the number of comprehensive screening programs in high-prevalence regions for sickle cell disease coupled with the growth in clinical trial activity is anticipated to elevate the market value in the coming years.

Vaso Occlusive Crisis Market Overview

Vaso occlusive crisis is considered the most common clinical manifestation of sickle cell disease. The frequency of crisis is reported to be extremely variable, with some individuals experiencing up to 6 or more episodes in a year. The increasing prevalence of sickle cell disease and the growing patient awareness are expected to augment the market demand for effective treatments. The market is also affected by the rising advancements in gene therapies and increased R&D expenditure by biotechnology and pharmaceutical companies. Moreover, the growth in clinical trial activity and robust regulatory support are some of the factors projected to positively influence the market dynamics in the coming years.

Vaso Occlusive Crisis Market Growth Drivers

Increasing Prevalence of Sickle Cell Disease Drives Market Growth

In the United States, sickle cell disease is reported to affect around 100,000 individuals, comprising over 90% non-Hispanic Black or African American and around 3-9% of Hispanics or Latinos. Further, the disease is highly prevalent in India, particularly among the tribal population. Since vaso occlusive crisis is one of the most common clinical manifestations of sickle cell disease, the rise in the number of such individuals is poised to boost the market growth in the forecast period. Additionally, this rising disease burden is anticipated to propel new drug development efforts for better management of vaso occlusive crisis.

Vaso Occlusive Crisis Market Trends

Vaso Occlusive Crisis Market Segmentation

The report offers a detailed analysis of the market based on the following segments:

Market Breakup by Treatment Type

  • Gene Therapy
  • Supportive Care

Market Breakup by Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Others

Market Breakup by Region

  • United States
    • EU-4 and the United Kingdom
    • Germany
    • France
    • Italy
    • Spain
    • United Kingdom
  • Japan
  • India

Vaso Occlusive Crisis Market Share

Market Segmentation Based on Treatment Type is Likely to Witness Substantial Growth

The market breakup by treatment type includes gene therapy and supportive care. The gene therapy segment is poised to dominate the market share owing to the rising advancements in CRISPR technology and other gene editing methods. Further, there is an increase in the number of clinical trials aimed at correcting the defective hemoglobin gene, which is likely to fuel the growth of this segment in the coming years.

Vaso Occlusive Crisis Market Analysis by Region

The market segmentation by region includes the United States, EU-4 (Germany, France, Italy, Spain), and the United Kingdom, Japan, and India. The United States holds a substantial market share which can be attributed to the presence of key market players and the high clinical activity in the region. The market also benefits from the increasing research funding for gene therapies and the growing demand for advanced therapies for vaso occlusive crisis. Moreover, the high healthcare spending and increased public awareness about sickle cell diseases are expected to boost the market growth in the region.

Leading Players in the Vaso Occlusive Crisis Market

The key features of the market report comprise patent analysis, grants analysis, clinical trial analysis, funding and investment analysis, and strategic initiatives by the leading key players. The major companies in the market are as follows:

Novartis AG

Headquartered in Basel, Switzerland, Novartis AG is counted among one of the largest pharmaceutical companies in the world. The company actively participates in strategic partnerships with both public and private sectors to advance sickle cell disease care across the globe.

Pfizer Inc.

Pfizer, established in 1849, is one of the leading players in the market. The company is known for its extensi...

AstraZeneca Plc

This British-Swedish multinational pharmaceutical and biotechnology company has a prominent presence in the ma...

Modus Therapeutics Holding AB

Modus Therapeutics, a Swedish biotechnology company, plays a significant role in the growth of the market. The...

Other key players in the market include Emmaus Life Sciences, Inc., Imara Inc., Sangamo Therapeutics, Inc., bluebird bio, Inc., and NuvOx Pharma LLC.

Key Questions Answered in the Vaso Occlusive Crisis Market Report

  • What was the vaso occlusive crisis market value in 2023?
  • What is the vaso occlusive crisis market forecast outlook for 2024-2032?
  • What are the regional markets covered in the EMR report?
  • What is market segmentation based on treatment type?
  • What is the market breakup based on the distribution channel?
  • What are the major factors aiding the vaso occlusive crisis market demand?
  • How has the market performed so far and how is it anticipated to perform in the coming years?
  • What are the market's major drivers, opportunities, and restraints?
  • Which regional market is expected to lead the market share in the forecast period?
  • Which country is expected to experience expedited growth during the forecast period?
  • How do the prevalence and incidence of sickle cell anemia affect the market landscape?
  • What are the major vaso occlusive crisis market trends?
  • How do the rising investments in gene therapies impact the market size?
  • Which treatment type will dominate the market share?
  • Which distribution channel is expected to have a high market value in the coming years?
  • Who are the key players involved in the vaso occlusive crisis market?
  • What is the patent landscape of the market?
  • What are the current unmet needs and challenges in the market?
  • How are partnerships, collaborations, mergers, and acquisitions among the key market players shaping the market dynamics?

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

REPORT FEATURES DETAILS
Base Year 2023
Historical Period 2017-2023
Forecast Period 2024-2032
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Treatment Type
  • Distribution Channel
  • Region
Breakup by Treatment Type
  • Gene Therapy
  • Supportive Care
Breakup by Distribution Channel
  • Hospital Pharmacies
  • Retail Pharmacies
  • Others
Breakup by Region
  • United States
  • EU-4 and the United Kingdom
  • Japan
  • India
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • PESTEL Analysis
  • Porter’s Five Forces Model 
  • Key Demand Indicators
  • Key Price Indicators
  • Industry Events, Initiatives, and Trends 
  • Value Chain Analysis
Supplier Landscape
  • Market Structure
  • Company Profiles
    • Financial Analysis
    • Product Portfolio
    • Demographic Reach and Achievements
    • Company News and Developments
    • Certifications
Companies Covered
  • Novartis AG
  • Pfizer Inc.
  • AstraZeneca Plc
  • Modus Therapeutics Holding AB
  • Emmaus Life Sciences, Inc.
  • Imara Inc.
  • NuvOx Pharma LLC
  • Sangamo Therapeutics, Inc.
  • bluebird bio, Inc.

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