Global Transplantation Market Report and Forecast 2024-2032

Global Transplantation Market Outlook

The global transplantation market size reached a value of USD 15.10 billion in 2023. The market is likely to grow at a rate of 9.4% in the forecast period of 2024-2032 to reach a market value of USD 33.89 billion by 2032. The increasing research and developmental activities, along with technological advancements are supporting the market growth.

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Transplantation: Overview, Types, Uses, and Segmentation

Transplantation is one of the most advanced and great advances in modern medicine. Transplantation is a procedure of removing organ, tissue, or cells from one subject and surgically placing it in another subject whose organ has failed. The former is called the donor, while the latter is referred to as a recipient. Transplantation is generally considered the last therapeutic intervention in cases of organ failure or damage due to any disease or injury.

The organs that can be donated include the heart, kidneys, pancreas, uterus, liver, lungs, and intestine. The tissues being transplanted from the healthy donor to the recipient are the bones, heart valves, skin patches, tendons, cornea, and nerves. Out of the tissues, cornea and musculoskeletal grafts are majorly transplanted, while kidneys are the most transplanted organs in the human body.

There are several types of transplants, including autograft, allograft, domino transplants, xenograft, and ABO-incompatible transplants. The organs or tissues can be donated from either a living or deceased donor. There has been the formulation of several laws and regulations in both developed and developing countries for enhancing the safety and availability of organ or tissue transplants to their citizens.

The transplantation market can be categorised into the following segments:

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Market Breakup by Product

• Transplant Preservative Solutions

• Transplant Diagnostics

• Tissue Products

• Immunosuppressive Drugs

• Others

Market Breakup by Type of Transplant

• Solid Organ Transplant
  • Kidney
  • Heart
  • Lungs
  • Liver
  • Intestine
  • Others
• Stem Cell Transplant
  • Autologous Transplants
  • Allogenic Transplants
• Tissue Transplant
  • Autografts
  • Allografts
• Others

Transplantation Market Breakup by Application

• Clinical Therapeutics

• Translational Research

• Diagnostic Purposes

• Others

Market Breakup by End User

• Hospitals

• Transplantation Centres

• Others

Market Breakup by Region

• North America
  • United States of America
  • Canada
• Europe
  • United Kingdom
  • Germany
  • France
  • Italy
  • Others
• Asia Pacific
  • China
  • Japan
  • India
  • ASEAN
  • Australia
  • Others
• Latin America
  • Brazil
  • Argentina
  • Mexico
  • Others
• Middle East and Africa
  • Saudi Arabia
  • United Arab Emirates
  • Nigeria
  • South Africa
  • Others

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Market Scenario

The growth of the transplantation market is driven by the rising cases of organ failure, which can be attributed to the growing incidence of acute and chronic diseases, including poisoning, trauma, leukaemia, and sepsis. This has led to increased demand for tissue and organ transplants and thus will facilitate market growth and development.

The emergence of unhealthy eating habits, increased consumption of alcohol, drug abuse and lack of physical exercise are also increasing the chances of organ failure. This is anticipated to accelerate the demand for organ or tissue transplants and will directly influence the growth of the transplantation market during the forecast period.

Tissue Products is Anticipated to Hold a Maximum Share

Tissue products are expected to hold a significant share in the market owing to the increasing number of transplantation procedures incorporating the application of tissue products, such as orthopaedic soft tissues, heart valves, and bone marrow. This is expected to attribute to the major share of this segment. The growing number of product launches and approvals and the rising number of mergers and acquisitions are also projected to fuel the market development.

North America Accounts for the Largest Share

North America is anticipated to dominate the transplantation market due to the well-developed healthcare facilities and the strategic presence of major pharmaceutical companies, like Arthrex, Zimmer Biomet, Stryker, Novartis, and Medtronic in the region. Further, the increasing initiatives by the government and other non-governmental organisations to aware people of organ donations are also expected to accelerate the market in the forthcoming years.

Therapeutic Landscape

Transplantation is a wide branch of modern medicine and is used for the treatment of several therapeutic indications. Tremendous efforts of scientists, researchers, and healthcare professionals have led to innovative transplantation methods that have helped to improve healthcare and the global economy.

One of the emerging therapies incorporating transplantation is cell transplantation or cell therapy. The therapeutic interventions include hematopoietic stem cell transplantation, neural stem cell therapy, and mesenchymal stem cell therapy. These therapies are utilized in the cases of myeloid malignancies, osteogenesis imperfecta, Hurler’s syndrome, and other haematological indications.

The transplantation of the entire bladder or the bladder tissue from a healthy donor to the recipient has also provided therapeutic effects in the management of renal disorders. The bladders are biosynthesized which can be then transplanted into the patient’s body. Kidney and liver transplants are being utilized in case of renal dysfunction and hepatic failure.

A heart transplant is used in patients suffering from congestive heart failure, for restoring the normal functioning of the heart. Other organ transplants including lung transplants are also used in the treatment of pulmonary disorders, wherein, one or both lungs have stopped functioning and the patient is expected to survive for less than two years.

Stem cell transplant is another transplantation technique which is applied for the management of the disease damaging the bone marrow cells. This type of transplant gives rise to novel blood cells, thus replacing the damaged cells in the body.

Clinical Trials Landscape

With extensive research and innovations, clinical researchers are working on discovering novel organ/tissue transplantations that would be useful in the treatment of novel therapeutic indications. The undergoing clinical trials are expected to utilize novel technologies and methods, that are more efficient therapeutically. 

In the United States, LyGenesis, a key market player is performing clinical trials for the novel technique, involves the development of ectopic livers. In this intervention, the cells are injected from the donor liver which is expected to form multiple mini livers thus, expected to keep the patient healthy. If successfully passed, this can be used for the management of patients suffering from end-stage liver disease.

A novel method of islet transplantation is under stage III clinical trials for testing the degree and effect of insulin independence in patients suffering from diabetes. In this method, the normal islet cells from the healthy donor are injected into the patient, which aids in the production of insulin and thus controls diabetes.

Paragonix technologies, a major market leader, has launched a novel organ tracking technology to make the entire in-transit of donor organs transparent. This will be used to capture the exact location of the device and thus, will help in early transportation and will increase the chances of saving the patient life.

The positive results of these trials, the invention of novel methods, better advancements and increased understanding and awareness will also propel the market expansion in the near future. 

Competitive Landscape:

The report gives an in-depth analysis of the key players involved in the market, sponsors manufacturing the drugs, and putting them through trials to get FDA approvals. The transplantation market companies included in the market are as follows:

• AbbVie Inc.

• Arthrex, Inc.

• Zimmer Biomet

• Medtronic

• Novartis AG

• Stryker

• 21st Century Medicine

• BioLife Solutions

• Teva Pharmaceutical Industries Ltd.

• Astellas Pharma Inc.

Key Highlights of the Report