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Report Overview

The global TIL therapies market was valued at USD 10.20 Million in 2024, driven by the growing incidence of cancer and the advancements in immunotherapy across the globe. The market is anticipated to grow at a CAGR of 12.00% during the forecast period of 2025-2034, with the values likely to reach USD 31.68 Million by 2034.

2024

Base Year

2018-2024

Historical Year

2025-2034

Forecast Year

  • In September 2024, KSQ Therapeutics' KSQ-004EX received Investigational New Drug status by the United States FDA. This CRISPR/Cas9-engineered TIL therapy provides a breakthrough in solid tumor treatments, extending the potential of tumor-infiltrating lymphocytes in cancer therapy.
  • Major market trends include innovation and a focus on improving the effectiveness of TIL-based cancer therapies by increasing focus on combining TIL therapies with other immunotherapies.
  • The leading players in the market are increasing their efforts in clinical trials, with many focusing on the development of new TIL products and pursuing strategic partnerships to enhance treatment availability and effectiveness.

TIL Therapies Market Overview

Tumor-infiltrating lymphocytes (TIL) therapies are a form of therapy that involves drawing immune cells, specifically T lymphocytes, from a patient's tumor, expanding the cells in a lab, and reinfusing them to target cancer cells. This approach is aimed at boosting the body's natural defense mechanism against tumors, offering promise for treating cancers such as melanoma. The field of immuno-oncology is rapidly advancing, as it focuses on using the body's immune cells to fight cancer. The market is poised for significant growth, with breakthroughs in the treatment of cancer, growth in funding for research, and an increasing number of clinical trials. The market will undergo significant development with transformative targeted therapies.

TIL Therapies Market Growth Drivers

Growing Incidence of Cancer to Boost the Market Growth

The increasing incidence of cancer is one of the major growth drivers of the market. As per the World Health Organisation, in 2022, there were around 20 million new cancer cases, and 9.7 million deaths occurred globally. This rising prevalence necessitates advanced treatments. Innovative therapies such as TIL, which are more targeted and less invasive, are gaining importance and thus contributing to growth in the market.

Advancements in Immunotherapy to Drive the TIL Therapies Market Value

Advancements in immunotherapy are one of the crucial growth drivers for the market. Innovations in immune cell engineering and a greater understanding of the tumor microenvironment significantly enhance the results of therapy. They have the advantages of being highly personalized and targeted, as well as a higher success rate than standard methods. Their rising adoption is the driving force behind the market's growth.

TIL Therapies Market Trends

TIL Therapies Market Segmentation

The market report offers a detailed analysis of the market based on the following segments:

Market Breakup by Type of Cell

  • T-Cells
  • B-Cells
  • Natural Killer Cells

Market Breakup by Indication

  • Cervical Cancer
  • Ovarian Cancer
  • Kidney Cancer
  • Gastrointestinal Cancer
  • Head and Neck Cancers

Market Breakup by Target Antigen

  • CD3
  • CD8
  • CD16
  • CD56
  • CD4
  • CD57
  • CD169
  • CD68
  • FOXP3

Market Breakup by End User

  • Hospital
  • Speciality Clinics
  • Cancer Hospital
  • Others

Market Breakup by Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

TIL Therapies Market Share

Segmentation Based on Type of Cell to Witness Substantial Growth

The market is segmented based on the type of cell including T-cells, B-cells, and natural killer cells. The T-cells are likely to account for a significant share of the market as they play a critical role in immune response. T-cells, particularly tumor-infiltrating lymphocytes, are one of the prime focuses of cancer immunotherapy, hence, showing high potential for various therapies in malignancies.

TIL Therapies Market Analysis by Region

The market is divided into regions such as North America, Europe, Asia Pacific, Latin America, and Middle East and Africa. North America is a major shareholder in the market, driven by a strong health infrastructural framework, a high incidence of cancer, and significant investments in immunotherapy research. Europe is the other key region, based on the increasing adoption of sophisticated cancer treatments and growing collaboration in research. Both regions are central to the TIL therapies development in the global market.

Leading Players in the TIL Therapies Market

The key features of the market report comprise patent analysis, clinical trial analysis, grants analysis, funding and investment analysis, and strategic initiatives by the leading players. The major companies in the market are as follows:

Autolus Therapeutics plc

Autolus Therapeutics is a United Kingdom-based company founded in 2014 and specializes in developing innovative T-cell therapies for cancer. It focuses on TIL therapies, and the lead product AUTO1, targeting acute lymphoblastic leukemia (ALL) has shown significant success. The company continues to advance CAR-T cell therapies, making a great contribution to TIL-based treatments for blood cancers.

Bellicum Pharmaceuticals, Inc.

Bellicum Pharmaceuticals was founded in the year 2004 with its headquarters in Houston, Texas. The c...

Eli Lilly and Company

Eli Lilly is a leader in pharmaceutical innovation which was founded in 1876 and has its headquarter...

Adaptimmune Therapeutics plc

Adaptimmune Therapeutics was founded in 2008 and is based in Oxford, United Kingdom. It is focused o...

*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*

Other key players in the market include Oxford Biomedica Plc., Precision Biosciences Inc., Seeking Alpha Ltd., Bluebird Bio, Inc., Fate Therapeutics Inc., and Merck KGaA.

Key Questions Answered in the TIL Therapies Market Report

  • What was the TIL therapies market value in 2024?
  • What is the TIL therapies market forecast outlook for 2025-2034?
  • What are the regional markets covered in the EMR report?
  • What is the market segmentation based on the type of cell?
  • What is the market segmentation based on indication?
  • What is the market breakup based on target antigen?
  • What is the market breakup based on the end user?
  • What major factors aid the TIL therapies market demand?
  • How has the market performed so far and how is it anticipated to perform in the coming years?
  • What are the major drivers, opportunities, and restraints in the market?
  • What are the major trends that influence the market?
  • Which regional market is expected to dominate the market share in the forecast period?
  • Which country is likely to experience elevated growth during the forecast period?
  • Who are the key players involved in the TIL therapies market?
  • What are the current unmet needs and challenges in the market?
  • How are partnerships, collaborations, mergers, and acquisitions among the key market players shaping the market dynamics?

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

REPORT FEATURES DETAILS
Base Year 2024
Historical Period 2018-2024
Forecast Period 2025-2034
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Type of Cell
  • Indication
  • Target Antigen
  • End User
  • Region
Breakup by Type of Cell
  • T-Cells
  • B-Cells
  • Natural Killer Cells
Breakup by Indication
  • Cervical Cancer
  • Ovarian Cancer
  • Kidney Cancer
  • Gastrointestinal Cancer
  • Head and Neck Cancers
Breakup by Target Antigen
  • CD3
  • CD8
  • CD16
  • CD56
  • CD4
  • CD57
  • CD169
  • CD68
  • FOXP3
Breakup by End User
  • Hospital
  • Specialty Clinics
  • Cancer Hospital
  • Others
Breakup by Region
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • PESTEL Analysis
  • Porter’s Five Forces Model 
  • Key Demand Indicators
  • Key Price Indicators
  • Industry Events, Initiatives, and Trends 
  • Value Chain Analysis
Supplier Landscape
  • Market Structure
  • Company Profiles
    • Financial Analysis
    • Product Portfolio
    • Demographic Reach and Achievements
    • Company News and Developments
    • Certifications
Companies Covered
  • Autolus Therapeutics plc
  • Bellicum Pharmaceuticals, Inc.
  • Eli Lilly and Company
  • Oxford Biomedica Plc.
  • Precision Biosciences Inc.
  • Seeking Alpha Ltd.
  • Bluebird Bio, Inc.
  • Adaptimmune Therapeutics plc
  • Fate Therapeutics Inc.
  • Merck KGaA

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