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The Sjogren’s syndrome treatment market was valued at USD 271.02 million in 2023, driven by increasing incidence of autoimmune diseases across the globe. The market is expected to grow at a CAGR of 3.79% during the forecast period of 2024-2032, with the values likely to reach USD 378.75 million by 2032.
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Sjogren’s syndrome is a chronic autoimmune disease characterized by the immune system attacking the glands responsible for production of tears and saliva. This condition results in dry eye and dry mouth (also known as sicca symptoms). Nevertheless, it can also affect other body parts like lungs, kidneys, joints, and nerves etc. leading to wide range of symptoms and complications. The treatment for the syndrome includes symptomatic treatment, biologic agents, immune system suppression, and lifestyle adjustments. Nearly 4 % of the world’s population is affected by one of more than 80 different autoimmune diseases.
Increasing Research and Development Activities
To curb the burden of the autoimmune disease, the market is witnessing increased research and development of new drugs. There is an increasing involvement of organizations in conducting clinical trials to produce a treatment for the syndrome to help the patients with Sjogren’s syndrome. In November 2023, Amgen presented data from phase 2 trial of dazodalibep, a CD40 ligand antagonist in Sjögren's syndrome at American College of Rheumatology. The clinical trial was a randomized, double-blind, placebo-controlled crossover study evaluating two Sjögren's populations. The findings from the study demonstrated positive results that dazodalibep may improve both the systemic and symptomatic disease burden of people living with Sjögren's syndrome.
Growth in Strategic Partnerships and Mergers to Meet Rising Sjogren’s Syndrome Treatment Market Demand
In February 2024, PrecisionLife and Metrodora Institute collaborated to diagnose and treat complex chronic diseases including long COVID, ME/CFS, ALS, Sjögren's syndrome, and many more. Under the agreement, both partners aim to first develop and validate genotypic diagnostics to provide clinicians with an accurate view of patients’ risk of disease. This involves using molecular profiling to understand the underlying disease mechanisms. The insights are projected to help clinicians in making more informed prescribing decisions and identify new areas for drug discovery leading to improve patient outcomes.
The market is witnessing several trends and developments to improve the current global scenario. Some of the notable trends are as follows:
Trends | Impact |
Shift Towards Personalized Medicines | Increasing preference for precision or personalized medicine for Sjogren’s syndrome can be observed in the market. Research on identifying genetics that might predict how a patient responds to specific medications. Biomarkers can be identified for better targeting and with tailored therapies, side effects can be minimized by selecting therapies that align more closely to an individual’s genetic makeup. |
Upgraded Diagnostic Tools | Early diagnosis with accuracy is a challenge in Sjogren’s syndrome as the symptoms overlap with other autoimmune diseases, therefore, advanced diagnostic tools are required. Conventional imaging system might not always detect subtle glandular changes; therefore, new imaging technique as salivary gland ultrasonography is being explored to detect structural changes. |
Increased Research Funding and Collaboration | Biotechnology and pharmaceutical companies are increasing investments to develop more effective treatment options for the syndrome, including non-pharmacological interventions and drug development. There is an increase in funding for well-designed clinical trials necessary for new drug development and to carter to the need of treatment options. |
Focus on Symptomatic Relief | The syndrome is marked by dryness of eyes and mouth along with joint fatigue that effects the quality of life. Symptomatic relief improves the daily life of a patient by improving comfort and functionality. The market consists of products that provide symptomatic relief, and the products are also being improved in terms of safety and efficacy. |
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Market Breakup by Drug Class
Market Breakup by Therapy Type
Market Breakup by Route of Administration
Market Breakup by Distribution Channel
Market Breakup by Region
Market Segmentation Based on Drug Class is Projected to Experience Substantial Growth
Based on drug class, the market segmentation includes antimalarial quinolines, cholinergic agents, corticosteroids among others. Antimalarial quinolones are majorly used for their anti-inflammatory properties that caters to the systemic symptoms of the syndrome. This segment is predicted to observe steady growth because of its efficacy in reducing skin rash and fatigue associated with the syndrome. To address the chief symptoms of Sjogren’s syndrome such as dry eyes and mouth, cholinergic agents are used as they stimulate the secretion of saliva. The demand for cholinergic agents is estimated to grow as the number of diagnosed cases are increasing, thereby increasing the requirement of symptomatic relief.
Corticosteroids are incorporated into the treatment regimen to control severe symptoms involving vital organs like kidneys and lungs. These medications are crucial in managing inflammation. Their use is limited to a short span of time as it can cause long term side effects.
Targeted Drug Therapy Expected to Lead the Market Share
Based on therapy type, the market constitutes targeted drugs, pain relievers, symptom modulators, vaccines, surgery, and others. Targeted drugs such as B cell-depleting agents and inhibitors of B cell activation offer precision treatment by aiming on molecular targets associated with the syndrome. To curb the pain and ease the symptoms, the pain relivers and symptom modulators are expected to witness significant growth. This is also attributed to the widespread use of symptom modulators are the primary concern for Sjogren’s syndrome is to get relief from the symptoms of dry mouth and dry eye. Surgical interventions, though less common, are crucial for severe cases where glandular functionality is heavily compromised.
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Regionally, the market report offers an insight into United States, EU-4 (including Spain, France, Italy and Germany) along with the United Kingdom, Japan and India. Leading the market with advanced healthcare infrastructure and investments in research and development, United States is projected to hold a significant market share in the forecast period. Increasing incidence of clinical trials in the region is also driving market growth in the region. Surge in investments in healthcare research and government support for innovations is boosting Europe’s Sjogren’s syndrome treatment market. The region also has a well-established infrastructure along with high awareness of autoimmune diseases.
The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.
REPORT FEATURES | DETAILS |
Base Year | 2023 |
Historical Period | 2017-2023 |
Forecast Period | 2024-2032 |
Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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Breakup by Drug Class |
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Breakup by Therapy Type |
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Breakup by Route of Administration |
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Breakup by Distribution Channel |
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Breakup by Region |
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Market Dynamics |
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Companies Covered |
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Sjogren’s Syndrome Treatment Market Size
Sjogren’s Syndrome Treatment Market Growth
Sjogren’s Syndrome Treatment Market Trends
Sjogren’s Syndrome Treatment Market Share
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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United States (Head Office)
30 North Gould Street, Sheridan, WY 82801
+1-415-325-5166
Australia
63 Fiona Drive, Tamworth, NSW
+61-448-061-727
India
C130 Sector 2 Noida, Uttar Pradesh 201301
+91-858-608-1494
Philippines
40th Floor, PBCom Tower, 6795 Ayala Avenue Cor V.A Rufino St. Makati City, 1226.
+63-287-899-028, +63-967-048-3306
United Kingdom
6 Gardner Place, Becketts Close, Feltham TW14 0BX, Greater London
+44-753-713-2163
Vietnam
193/26/4 St.no.6, Ward Binh Hung Hoa, Binh Tan District, Ho Chi Minh City
+84-865-399-124
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