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The global pyrosequencing market is expected to grow at a CAGR of 11.80% between 2024 and 2032, driven by increased demand for DNA sequencing, and applications in drug development and other fields across the globe.
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Pyrosequencing (based on “sequencing by synthesis” principle) is a DNA sequencing technology, which involves adding nucleotides to the complementary DNA template. It can be used to detect DNA and RNA presence from any source. It occurs in 6 major steps and primarily focuses on detecting the light emitted during sequential incorporation of nucleotides.
Pyrosequencing is involved multiple research and development domains, including pharmaceutical research, finding biomarker and diagnostics, and most importantly, molecular medicine and genetics. It is a powerful tool in genomics and many molecular biology studies as well. The market is witnessing increased infrastructure developments to integrate latest technologies and develop effective therapeutic alternatives for unmet patient needs. One of the significant factors boosting market growth include rising merger and acquisition activities in the biotech domain.
Increasing Demand for Personalized Medicine
Medicine is moving towards personalization. Precision medicine emerging field in healthcare as it helpps in generating treatments based on the patient’s genetic make-up, and lifestyle. The increasing prevalence of chronic diseases are driving the demand for personalised medicines among patients for more effective and long-term results. Personalised medicines and treatments typically require accurate DNA sequencing for optimum results, ultimately leading to the growth of the market for pyrosequencing.
Growing Application of Pyrosequencing in Healthcare Diagnostics
Pyrosequencing and its use as a sequencing-by-synthesis technique is rapidly gaining popularity in the field of diagnostics. Pyrosequencing is a key in healthcare diagnostics as it has gained a reputation in providing huge amount of accurate DNA data at high speed. It identifies many diseases, ranging from cancer to infectious diseases as well as genetic diseases. Its accuracy and ability to process signal easily makes it one of the best tools for diagnostics in precision medicine and drug development. This versatility is amongst the key factors driving its gradual expansion in healthcare.
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Key Trends | Impact |
Advancements in Biomarker Discovery | Pyrosequencing is proving to be useful in biomarker identification, which is vital in the development of medicine. The technology is accurate in finding certain genetic markers, linked to specific diseases. Hence, leading to enhanced disease management and cure. |
Adoption in Clinical Trials | Pyrosequencing is becoming the top study technique in clinical trials. It is used to study genetic factors. These factors may influence how drugs move in and affect the body, making patient stratification more efficient by using their genetic material. Therefore, it helps in creating better models for clinical trials. |
Integration with Bioinformatics | Technical improvements in pyrosequencing, along with integration of more sophisticated bioinformatics tools, are providing better means of analysis and data interpretation. Using bioinformatics algorithms and software is critical to interpret vast quantities of genomic data. |
Expansion of Next-Generation Sequencing (NGS) Technologies | The current trends and developments in next-generation sequencing (NGS) technologies have a big impact on the pyrosequencing industry. Pyrosequencing is improving speed, cost, and reliability, making NGS more useful for clinical research and routine diagnosis. |
In November 2023 -Illumina, Inc., launched Global Health Access to provide sequencing tools for public health in poor nations. This drive is expected to unite complex sequencing technologies and leverage it in identifying diseases and tracking epidemics. It can also help in treating patients by addressing their specific needs to reduce health disparity across various economic demographics.
In August 2023, PacBio announced a research partnership with the University of Washington to study HiFi long-read whole-genome sequencing (WGS). The partnership aimed to make more analyses show real genomics of genetic diseases. Such alliances are intended to meet healthcare needs and boost the sequencing market growth.
Market Breakup by Type
Market Breakup by Application
Market Breakup by End User
Market Breakup by Region
Market Breakup Based on End User Set to Witness Growth
The market segmentation by end-users include hospitals, speciality clinics, research centers and academic institutes, among others. Hospitals and speciality clinics are identified as key end-users within the pyrosequencing market. They interact with patients and collect sample for genetic analysis and are also involved in launching customized medicine programs. As chronic diseases like cancer, hepatitis B, and liver diseases are becoming more common along with the emergence of infection-prone diseases, there is a trend for personalized treatment. This in turn boosts the market value for pyrosequencing technologies. Research centers also use pyrosequencing for many applications, including drug discovery, controlling bacterial resistance, and epigenomic assays. There has been an enormous investment in high-resolution research and developments, likely to impact the market value for research centers in the forecast period.
Diagnostics are Expected to Lead Market Share Based on Application
Based on application, the market is divided into drug discovery, biomarker discovery, diagnostics, personalized medicine, and others. Diagnostics are expected to account for a significant market share in the forecast period, driven by the ability of pyrosequencing to offer fast and accurate diagnosis of many diseases, such as cancer, infections, and genetic diseases such as dysmorphology, among others. Drug discovery uses pyrosequencing to enhance the rate new drug development. Pharmacogenomics remains an innovative and flourishing field, with its approach centered on pyrosequencing, as it enables to provide personalized strategies.
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Based on region, the market is divided into North America, Europe, Asia Pacific, Latin America, along with the Middle East, and Africa. North America is expected to hold the largest market share due to the high usage of analytical and diagnostic techniques in the medicine and research domain. Healthcare providers possess high knowledge about customized care. Such factors play a critical role in boosting the market value in the region.
Other regions such as Europe and Asia Pacific are expected to experience substantial market growth, driven by the use of new techniques in pyrosequencing applications. Asia Pacific is likely to witness a steep rise in pyrosequencing, driven by the emphasis on improving patient outcomes by improving healthcare infrastructure across the region.
The key features of the market report include patent analysis, funding and investment analysis, and strategic initiatives such as partnerships, and collaborations analysis by the leading players. The major companies in the market are as follows:
QIAGEN N.V.
It is a German corporation It focuses on technology solutions. Its headquarters are in Hilden, Germany. The company began in 1984. It offers products such as assays and samples. They are for use in test systems, molecular diagnostics, and research at pharmaceutical and academic research.
Biotage AB
It was established in 1969, and it is in Uppsala, Sweden. This is a life science company. It focuses on combining and splitting technologies to affect processes. They offer services in areas such as peptide synthesis, medicinal and analytical chemistry, purification, separation, and chromatography.
Lumitos AG
Established in 2000, and headquartered in Berlin, Germany. This online media company supports various segments. They include life science, food and beverages, chemicals, pharmaceuticals, and medicines. They use traditional online methods.
AAT Bioquest, Inc.
The company was established in 2005 and has it headquarter in California, United States. The company deals in pyrosequencing kits that consist of reagents and consumables as well as sequencing primers that are optimized for the sequencing technique, nucleotide substrates of high quality, pyro sequencers that are instrumental in the sequencing process, and other related goods and materials such as reaction plates and pipette tips.
Other companies in the market include EpigenDX, Molecular Research LP, ATDBio Limited (Biotage).
Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.
REPORT FEATURES | DETAILS |
Base Year | 2023 |
Historical Period | 2017-2023 |
Forecast Period | 2024-2032 |
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Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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Breakup by Application |
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Breakup by End User |
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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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