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Report Overview
2023
Base Year
2017-2023
Historical Year
2024-2032
Forecast Year
Global Protein Expression Market Outlook
The global protein expression market size was valued at USD 3 billion in 2023, driven by the increased protein-based research and development activities across the globe. The market is expected to grow at a CAGR of 5.40% during the forecast period of 2024-2032, with the values likely to rise from USD 3.2 billion in 2024 to USD 4.9 billion by 2032.
Global Protein Expression Market Overview
The increased impetus on therapeutic proteins in modern medicine along with the robust research and development activities is positively impacting the market landscape. To manufacture various protein-based pharmaceutical products, several expression systems have been developed. Recent advancements have made it possible to produce therapeutic proteins against cancers and infectious diseases, which is expected to boost the protein expression market demand in the forecast period.
The market is witnessing significant investments from the key market players to accommodate the growing demand for personalized medicines. In February 2024 , BioAscent, a United Kingdom-based pharmaceutical company invested in a new protein production facility to enable in-house production of proteins. A major portion of the investment was made in specialized equipment including FPLC (fast protein liquid chromatography). The facility, with a team of skilled protein scientists, will be dedicated to the expression and purification of proteins from various expression systems. Such investments will accelerate the timelines of drug discovery projects and will contribute to the protein expression market growth in the coming years.
The market is also driven by the growing demand for protein biologics and the adoption of recombinant-based protein expression. Moreover, the rise in the prevalence of chronic diseases necessitating the development of effective therapeutics is propelling the market growth.
Global Protein Expression Market Trends
| Key Trends | Description |
| Advancements in Protein Expression Technologies | The significant improvements in protein expression technologies have enabled more efficient, scalable, and cost-effective protein production, catering to the increasing demand for therapeutic proteins, vaccines, and for use in research applications. |
| Rise in Chronic Diseases | The global increase in the prevalence of chronic diseases such as cancer, diabetes, and autoimmune disorders has increased the demand for protein-based therapeutics. This trend is directly influencing the growth of the protein expression market, as proteins are involved in both the study and treatment of various conditions. |
| Expansion in the Biologics Market | The growing pipeline of biologics, including monoclonal antibodies, vaccines, and gene therapies, is driving the need for robust protein expression systems. This is because protein expression technologies are needed for the development and manufacturing of these complex biological products. |
| Growing Interest in Personalized Medicine | The need for protein expression in small-scale, patient-specific batches is pushing the market towards more flexible and efficient expression systems capable of producing a wide variety of proteins. |
Global Protein Expression Market Segmentation
Market Breakup by Type of Expression System
- Bacterial Expression Systems
- Mammalian Expression Systems
- Yeast Expression Systems
- Insect Expression Systems
- Cell-Free Expression Systems
- Algal Expression Systems
- Other Expression Systems
The market is segmented by the type of expression system into bacterial expression systems, mammalian expression systems, yeast expression systems, insect expression systems, cell-free expression systems, algal expression systems, and other expression systems. These systems are widely used in research institutes and industries to enable the production of proteins for various applications.
Market Breakup by Product Type
- Reagents
- Expression Vectors
- Competent Cells
- Instruments
- Services
By product type, the protein expression market share is divided into reagents, expression vectors, competent cells, instruments, and services. These products and services support the efficient production and manipulation of proteins.
Market Breakup by Application
- Therapeutic Proteins
- Research Applications
- Industrial Proteins
- Diagnostic Proteins
- Others
Applications of the market include therapeutic proteins, research applications, industrial proteins, diagnostic proteins, and others. The increased application of protein expression in various sectors including drug development, scientific research, and industrial processes is boosting the market size.
Market Breakup by Technique
- Ion Exchange Chromatography
- Hydrophobic Interaction Chromatography (HIC)
- Affinity Chromatography
- Size Exclusion Chromatography
- Others
Based on the technique, the protein expression market report includes ion exchange chromatography, hydrophobic interaction chromatography (HIC), affinity chromatography, size exclusion chromatography, and others. Depending on the properties of the proteins, these techniques are employed for protein purification and separation.
Market Breakup by Cell Type
- Mammalian Cells
- Bacterial Cells
- Yeast Cells
- Insect Cells
- Algal Cells
- Cell-Free Systems
The market is segmented by cell type into mammalian cells, bacterial cells, yeast cells, insect cells, algal cells, and cell-free systems. These cell types serve as host systems for protein expression for various applications in research and pharmaceutical industries, among others.
Market Breakup by End User
- Biotechnology and Pharmaceutical Companies
- Academic Research Institutes
- Contract Research Organizations (CROs)
- Others
Based on the end user, the protein expression market share includes biotechnology and pharmaceutical companies, academic research institutes, contract research organizations (CROs), and others. These end users drive demand for protein expression products and services.
Market Breakup by Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East and Africa
The market report offers deep insights into the major regional markets which include North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. North America holds a high market value due to the rapid advancement in the healthcare infrastructure. The market is also driven by the presence of premium research institutes and leading market players contributing actively to the growing market share.
Global Protein Expression Market: Competitor Landscape
The key features of the market report include patent analysis, grants analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
- Thermo Fisher Scientific, Inc.
- Merck KGaA (Sigma-Aldrich Corporation)
- Agilent Technologies, Inc.
- Bio-Rad Laboratories, Inc.
- QIAGEN N.V.
- Lonza Group AG
- Genscript Biotech Corporation
- Takara Bio Inc.
- Promega Corporation
- New England Biolabs
- Oxford Expression Technologies Ltd. (OET)
- Synthetic Genomics, Inc.
- Biomatik Corporation
- Cayman Chemical Company
- Zymo Research Corporation
Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.
Key Highlights of the Report
| REPORT FEATURES | DETAILS |
| Base Year | 2023 |
| Historical Period | 2017-2023 |
| Forecast Period | 2024-2032 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
|
| Breakup by Type of Expression System |
|
| Breakup by Product Type |
|
| Breakup by Application |
|
| Breakup by Technique |
|
| Breakup by Cell Type |
|
| Breakup by End User |
|
| Breakup by Region |
|
| Market Dynamics |
|
| Supplier Landscape |
|
| Companies Covered |
|
Key Queries Solved in the Global Protein Expression Market Report
- What are the current trends driving the global protein expression market?
- Which factors are influencing the growth of protein expression technologies?
- What are the key challenges faced by stakeholders in the protein expression market?
- Which type of protein expression system is expected to dominate the market segment?
- What are the applications and end-users driving demand in the protein expression market?
- Which applications are expected to significantly impact the protein expression market demand?
- Which cell type is expected to dominate the market demand?
- Which regions are witnessing significant growth in the protein expression market?
- What are the regulatory frameworks impacting the protein expression market?
- How is technological advancement shaping the future of the protein expression market?
- How is the integration of automation and artificial intelligence influencing protein expression research and production?
- What are the emerging opportunities for players in the protein expression market?
- What are the competitive landscape and key strategies adopted by leading companies?
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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Key Questions Answered in the Report
The market attained a value of about USD 3 billion in 2023 driven by the increased protein-based research and development activities across the globe.
The market is anticipated to grow at a CAGR of 5.40% during the forecast period of 2024-2032, likely to reach a market value of USD 4.9 billion by 2032.
The growing preference for personalized medicines and the increased healthcare expenditure are fuelling the demand for the market.
One of the significant trends in the market is the rising investments from the key market players. In February 2024 , BioAscent, invested in a new protein production facility to facilitate in-house production of proteins. The facility, with a team of skilled protein scientists, will be dedicated to the expression and purification of proteins from various expression systems.
The market is segmented by the type of expression system into bacterial expression systems, mammalian expression systems, yeast expression systems, insect expression systems, cell-free expression systems, algal expression systems, among other expression systems.
Based on the technique, the market includes ion exchange chromatography, hydrophobic interaction chromatography (HIC), affinity chromatography, size exclusion chromatography, and others.
Based on the product type, the market is segmented into reagents, expression vectors, competent cells, instruments, and services.
The market is segmented by cell type into mammalian cells, bacterial cells, yeast cells, insect cells, algal cells, and cell-free systems.
Major end users of the market include biotechnology and pharmaceutical companies, academic research institutes, contract research organizations (CROs), and others.
Applications of the market include therapeutic proteins, research applications, industrial proteins, diagnostic proteins, and others.
The major regions of the market include North America, Europe, Asia Pacific, Latin America, Middle East, and Africa.
Key players involved in the market are Thermo Fisher Scientific, Inc., Merck KGaA (Sigma-Aldrich Corporation), Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., QIAGEN N.V., Lonza Group AG, Genscript Biotech Corporation, Takara Bio Inc., Promega Corporation, New England Biolabs, Oxford Expression Technologies Ltd. (OET), Synthetic Genomics, Inc., Biomatik Corporation, Cayman Chemical Company, and Zymo Research Corporation.
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