The polycystic kidney disease drugs market was valued at USD 0.51 billion in 2024, driven by rising incidence of autosomal dominant polycystic kidney disease across the 8 major markets. The market is expected to grow at a CAGR of 5.90% during the forecast period of 2025-2034, with the values likely to reach USD 0.86 billion by 2034.
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Polycystic kidney disease (PKD) drugs are designed to address the formation of fluid-filled cysts in kidneys, which can lead to kidney dysfunction. The rising prevalence of PKD and the urgent need for effective treatments are driving market growth. The application of advanced technologies such as artificial intelligence and machine learning to generate high efficacy drugs is expected to impact the market landscape significantly. In addition, continued research initiatives, focused on significantly enhancing the scope and growth of the PKD drugs is amongst the major market trends.
Increasing Prevalence of Polycystic Kidney Disease (PKD) to Affect the Market Landscape Significantly
Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of polycystic kidney disease, affecting 1 in 500 to 1,000 individuals globally. It is especially exacerbated by diabetes and hypertension. Consequently, rising prevalence of diabetes and obesity, which can be attributed to sedentary lifestyle and lack of an exercise regime can lead to heightened demand for polycystic kidney disease drugs in the coming years.
Surge in FDA Approvals to Meet Rising Polycystic Kidney Disease Drugs Market Demand
In September 2023, the United States FDA approved Eli Lilly’s Jardiance® (empagliflozin) 10 mg tablets for the treatment of chronic kidney disease (CKD). This approval introduced a promising treatment option for over 35 million affected adults, marking a substantial milestone in CKD management. Empagliflozin demonstrated efficacy in slowing CKD progression, as evidenced in the EMPA-KIDNEY phase III trial, and included a notable reduction in hospitalization risks as well.
The market is witnessing several trends and developments to improve the current global scenario. Some of the notable trends are as follows:
| Key Trends | Impact |
| Adoption of Innovative Methodologies to Develop Effective Drugs | The persistent lack of targeted therapies to halt cyst growth and preserve kidney function underscores the urgent need for innovation drug development in PKD, potentially reshaping treatment approaches. |
| Suge in Research Efforts | Expanding research endeavors into PKD pathophysiology hold the potential to revolutionize treatment paradigms by unravelling novel therapeutic targets and paving the way for precision medicine tailored to individual patient profile. |
| Advancements in Technology | Technological innovations like high-output screening and computational modeling expedite the identification and optimization of potential PKD drug candidates. Such advancements usher in next-generation treatments with enhanced efficacy and safety profiles. Drug repurposing intended to recognize new clinical indications for approved or investigational medications is being employed in drug development, attributed to its cost efficiency and time saving benefits. |
| Increasing Preference for Personalized medicines | The increasing adoption of personalized medicine approaches, leveraging genomics and biomarker to reshape PKD drugs is a significant market trend. It can enable tailored therapeutic interventions based on individual patient characteristics, ultimately enhancing patient care and quality of life. |
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The EMR’s report titled “Polycystic Kidney Disease Drugs Market Report and Forecast 2024-2032” offers a detailed analysis of the market based on the following segments:
Market Breakup by Disease Type
Market Breakup by Route of Administration
Market Breakup by Distribution Channel
Market Breakup by Region
Autosomal Dominant Polycystic Kidney Disease (ADPKD) Leads the Market Share Based on Type
The market segmentation based on disease type is divided into autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD). Out of these, ADPKD emerges as the predominant leader in the polycystic kidney disease drugs market. Its high prevalence among PKD cases secures a significant market share, surpassing its rare counterpart, autosomal recessive polycystic kidney disease (ARPKD).
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The market for polycystic kidney disease drugs spans across United States, EU-4 (Germany, France, Italy and Spain), the United Kingdom, Japan and India, with each region significantly contributing to its dynamics. United States stands out as a market leader. Its market value due can be accredited to higher prevalence of PKD in the region. Having a robust regulatory infrastructure also adds notable value. In March 2024, Vertex Pharmaceuticals (VRTX ) received U.S. Food and Drug Administration (FDA) approval for VX- 407, an investigational drug targeting ADPKD. VX-407 is a small molecular corrector, which addresses the underlying cause of ADPKD in patients with specific PKD1 genetic variants.
ADPKD is the most common inherited kidney disease that affects an estimated 250,000 individuals in the United States and Europe combined. Consequently, Europe also holds a significant market share for polycystic kidney disease drugs. In Europe, the presence of affluent research institutions along with a well-established research infrastructure play a critical role in boosting the market value.
They key features of the market report include patent analyses, grants analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
F. Hoffmann-La Roche Ltd, headquartered in Basel, Switzerland, was founded in 1896. The company specializes in pharmaceutical manufacturing and is a leader in the field of cancer drug development and sales. Roche has developed drugs and diagnostics for various disease, including PKD-1 inhibitors. Some of the drugs include Mycophenolate Mofetil (Cellcept), and Valganciclovir (Valcyte).
Galapagos NV, founded in 1999 as a joint venture between Crucell and Tibotec, is headquartered in Me...
Johnson & Johnson Services, Inc. was established in 1886 in New Brunswick. The company is developing...
Merck and Co. Inc. was founded in 1891, in New York. The company is amongst the leading companies in...
*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*
Other companies in the market include AbbVie Inc., Apotex Inc., Amgen Inc., Otsuka Holdings Co. Ltd., Palladio Biosciences Inc., Regulus Therapeutics, Sanofi SA, XORTX Therapeutics Inc., Novartis AG, Teva Pharmaceutical Industries Ltd, and Bayer AG.
Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.
Polycystic Kidney Disease Drugs Market Size
Polycystic Kidney Disease Drugs Market Growth
Polycystic Kidney Disease Drugs Market Trends
Polycystic Kidney Disease Drugs Market Share
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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| REPORT FEATURES | DETAILS |
| Base Year | 2024 |
| Historical Period | 2018-2024 |
| Forecast Period | 2025-2034 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Disease Type |
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| Breakup by Route of Administration |
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| Breakup by Distribution Channel |
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| Breakup by Region |
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| Market Dynamics |
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| Supplier Landscape |
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| Companies Covered |
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United States (Head Office)
30 North Gould Street, Sheridan, WY 82801
+1-415-325-5166
Australia
63 Fiona Drive, Tamworth, NSW
+61-448-061-727
India
C130 Sector 2 Noida, Uttar Pradesh 201301
+91-858-608-1494
Philippines
40th Floor, PBCom Tower, 6795 Ayala Avenue Cor V.A Rufino St. Makati City, 1226.
+63-287-899-028, +63-967-048-3306
United Kingdom
6 Gardner Place, Becketts Close, Feltham TW14 0BX, Greater London
+44-753-713-2163
Vietnam
193/26/4 St.no.6, Ward Binh Hung Hoa, Binh Tan District, Ho Chi Minh City
+84-865-399-124
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