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Global mRNA Vaccines and Therapeutics Market Size, Share: By Product: Vaccines, Drugs; By Application: Cancer, Infectious Disease, Rare Genetic Disease, Respiratory Disease, Others; By Treatment Type: Gene Therapy, Cell Therapy, Monoclonal Antibody, Others; By End User; Regional Analysis; Supplier Landscape; 2024-2032
Global mRNA Vaccines and Therapeutics Market Size
The global mRNA vaccines and therapeutics market was valued at USD 64.5 billion in 2023, driven by the rising incidence of chronic diseases and increasing awareness of the widespread potential of mRNA technology across the globe. The market is expected to grow at a CAGR of 1.20% during the forecast period of 2024-2032, with the values to reach USD 71.7 billion by 2032.
mRNA Vaccines and Therapeutics Market Outlook
- In November 2023, Japan approved ARCT-154, the first self-amplifying mRNA (sa-mRNA) COVID-19 vaccine globally. The vaccine is developed by CSL and Arcturus Therapeutics, registering a significant milestone in vaccine innovation.
- In March 2024, Strand Therapeutics discovered an improved class of mRNA molecules, designed to detect types of encountered cells and target diseased cells.
- The global prevalence of non-communicable diseases (NCDs) drives market growth for mRNA vaccines and therapeutics.
mRNA Vaccines and Therapeutics Market Overview
mRNA vaccines and therapeutics utilise messenger RNA molecules to instruct cells to produce proteins that trigger immune responses or treat diseases. The market is poised to be driven by rapid vaccine development, expanding applications of mRNA technology beyond infectious diseases, technological advancements enhancing efficacy and safety, increasing investments from public and private sectors, and regulatory support for innovative mRNA-based treatments. These factors collectively propel market growth, revolutionising healthcare with promising therapeutic innovations.
mRNA Vaccines and Therapeutics Market Growth Factors
Prevalence of Chronic Diseases Aiding the Market Demand
The market is poised for substantial growth due to the rising prevalence of chronic diseases globally. As per the data released by the World Health Organization, non-communicable diseases NCD claims nearly 41 million people per year which is approximately equivalent to 74% of all deaths worldwide.
The most common medical conditions that are the common cause of high deaths include cardiovascular diseases accounting for most NCD deaths, or 17.9 million people each year, followed by cancers (9.3 million), chronic respiratory diseases (4.1 million), and diabetes (2.0 million).
The rapidly changing lifestyle habits among people including tobacco consumption, physical inactivity, excess alcohol intake, unhealthy diets, and air pollution are categorised as common risk factors of NCDs.
Surge in Research and Development Initiatives to Boost mRNA Vaccines and Therapeutics Market Demand
In March 2024, MIT spinout Strand Therapeutics made significant advancements in the field of mRNA technology by developing a new class of mRNA molecules. It is capable of sensing the type of cells they encounter in the body and expressing therapeutic proteins specifically in diseased cells.
The success of such research initiatives may contribute to a surge in targeted mRNA therapies, accelerating regulatory approvals and adoption in healthcare settings. The market is anticipated to experience significant expansion in the mRNA therapeutics domain as these technologies become pivotal in treating chronic diseases like cancer further validating mRNA as a versatile and powerful tool in precision medicine.
Approvals by the Regulatory Authorities Solidifying the Market Demand
In November 2023, CSL, a global biotechnology leader and Arcturus Therapeutics announced that ARCT-154, a self-amplifying mRNA (sa-mRNA) COVID-19 vaccine for initial vaccination and booster for adults 18 years and older was approved by Japan's Ministry of Health, Labor and Welfare (MHLW). The approval of this vaccine recorded a significant milestone as the first sa-mRNA vaccine in the world. The approval by the MHLW supported the wider applications of the vaccine beyond COVID-19, owing to its efficacy and safety. The approval may also trigger regulatory authorities across the globe to approve similar mRNA treatments and vaccines to enable easy availability, boosting market growth. Underscoring the hidden potential of mRNA technology in developing medical treatments and public health, the market is poised to be propelled for an upward trajectory in the forecast period.
mRNA Vaccines and Therapeutics Market Trends
| Key Trend | Impact |
| Expanding Application | The market is witnessing continuous research and innovation in mRNA technology which is expected to discover new therapeutic opportunities. The research activities may find widespread applications beyond COVID-19, such as regenerative medicine, tissue engineering, and gene therapy. |
| Technological Advancements | Technological advancements are enabling the development of new and improved mRNA therapeutics in the market. The introduction of improved mRNA delivery systems, formulation techniques, and manufacturing processes are leading to enhanced efficacy, stability, and scalability of mRNA-based products. |
| Personalised Medicine | The escalating demand for personalised medicine is contributing to market growth. Personalised medicine enables the development of targeted therapies with increased efficacy and reduced side effects, compared to conventional treatments. |
| Increasing Investments | The substantial efficacy and validation of mRNA vaccines have attracted significant investment and funding into companies and research organisations working on mRNA-based technologies. This influx of capital is fueling research and development activities, driving innovation in the mRNA market. |
mRNA Vaccines and Therapeutics Market Segmentation
Market Breakup by Product
- Vaccines
- Self-amplifying mRNA-Based Vaccines
- Conventional Non-amplifying mRNA-Based Vaccines
- Drugs
Market Breakup by Treatment Type
- Gene Therapy
- Cell Therapy
- Monoclonal Antibody
- Others
Market Breakup by Application
- Cancer
- Infectious Disease
- Rare Genetic Disease
- Respiratory Disease
- Others
Market Breakup by End User
- Hospitals and Clinics
- Research & Development Organizations
- Others
Market Breakup by Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East and Africa
mRNA Vaccines and Therapeutics Market Share
Vaccines Dominate the Product Segment
The product segments include vaccines and drugs. Vaccines are further segmented into self-amplifying mRNA-based vaccines and conventional non-amplifying mRNA-based vaccines. Self-amplifying mRNA-based vaccines stand out due to their potential for enhanced immunogenicity, longer-lasting immune responses, and scalability in manufacturing. Vaccines dominate the product segment as they play a critical role in preventing infectious diseases and supporting public health. With the global emphasis on immunization, vaccines represent a foundation of preventive medicine, offering cost-effective and scalable solutions to fight a wide range of pathogens and protect global population.
Market Segmentation Based on Application Areas
Under application segmentation, there is cancer, infectious disease, rare genetic disease, respiratory disease, and others. The mRNA technology provides a promising approach towards personalized cancer immunotherapy, with continuous research focusing on its efficacy, safety, and therapeutic benefits.
mRNA Vaccines and Therapeutics Market Analysis by Region
Based on the regional analysis, the market report covers North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa, with each region contributing to the overall dynamics of the market. North America leads the market due to robust research and development activities along with a favorable regulatory environment. Europe is following North America driven by the increasing investments in mRNA technology. Asia-Pacific is poised to witness significant growth with rising healthcare expenditure and expanding biotech sector.
Leading Players in the Global mRNA Vaccines and Therapeutics Market
The key features of the market report include patent analysis, grants analysis, funding and investment analysis, clinical trials analysis and strategic initiatives by the leading key players. The major companies in the market are as follows:
AstraZeneca
Based out of Cambridge, United Kingdom, AstraZeneca has a strong focus on the discovery, development, and commercialization of prescription medicines. The company is continuing to expand its mRNA technology through collaborations and develop effective solutions in several therapeutic areas.
Pfizer Inc.
Established in 1849, Pfizer Inc., is one of the leading healthcare companies boasting a strong research and development department. The company collaborated with BioNTech and prepared one of the very first mRNA-based vaccines for COVID-19, known as BNT162b2 or Comirnaty.
Sangamo Therapeutics
It is a biotechnology company based in California, USA. The company is focused on developing genomic medicines with the help of its several proprietary technology platforms in gene therapy, gene editing, cell therapy, and genome regulation.
Other companies in the market include Moderna, Inc., Sanofi, Argos Therapeutics, GlaxoSmithKline plc., Gennova Biopharmaceuticals Limited, DAIICHI SANKYO COMPANY, LIMITED and Boehringer Ingelheim International GmbH.
Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.
Key Highlights of the Report
| REPORT FEATURES | DETAILS |
| Base Year | 2023 |
| Historical Period | 2017-2023 |
| Forecast Period | 2024-2032 |
| Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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| Breakup by Product |
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| Breakup by Application |
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| Breakup by Treatment Type |
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| Breakup by End User |
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| Breakup by Region |
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| Market Dynamics |
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| Supplier Landscape |
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| Companies Covered |
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Key Queries Solved in the Global mRNA Vaccines and Therapeutics Market Report
- What was the global mRNA vaccines and therapeutics market value in 2023?
- What is the global mRNA vaccines and therapeutics market forecast outlook for 2024-2032?
- What are the major factors aiding the global market demand?
- What are the major global market trends?
- What is the market segmentation based on the product?
- What are the major treatment types of mRNA vaccines and therapeutics?
- What are the application areas of mRNA vaccines and therapeutics?
- What are the major end users of the market?
- What are the major regional markets according to the EMR report?
- Who are the key players involved in the global mRNA vaccines and therapeutics market?
- How will the market landscape evolve in the upcoming years?
- What are the major drivers, opportunities, and restraints in the market?
- What will be the effect of each driver, challenge, and opportunity on the market?
- Which country is poised to lead the market share in the forecast period?
- Which distribution channel is anticipated to propel the market growth?
- Which segment has the highest impact on the market size?
- How are partnerships, collaborations, mergers and acquisitions shaping the market dynamics?
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.
1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Global mRNA Vaccines and Therapeutics Market Overview
3.1 Global mRNA Vaccines and Therapeutics Market Historical Value (2017-2023)
3.2 Global mRNA Vaccines and Therapeutics Market Forecast Value (2024-2032)
4 Vendor Positioning Analysis
4.1 Key Vendors
4.2 Prospective Leaders
4.3 Niche Leaders
4.4 Disruptors
5 Global mRNA Vaccines and Therapeutics Market Landscape*
5.1 Global mRNA Vaccines and Therapeutics: Developers Landscape
5.1.1 Analysis by Year of Establishment
5.1.2 Analysis by Company Size
5.1.3 Analysis by Region
5.2 Global mRNA Vaccines and Therapeutics: Product Landscape
5.2.1 Analysis by Product
5.2.2 Analysis by Application
6 Global mRNA Vaccines and Therapeutics Market Dynamics
6.1 Market Drivers and Constraints
6.2 SWOT Analysis
6.2.1 Strengths
6.2.2 Weaknesses
6.2.3 Opportunities
6.2.4 Threats
6.3 PESTEL Analysis
6.3.1 Political
6.3.2 Economic
6.3.3 Social
6.3.4 Technological
6.3.5 Legal
6.3.6 Environment
6.4 Porter’s Five Forces Model
6.4.1 Bargaining Power of Suppliers
6.4.2 Bargaining Power of Buyers
6.4.3 Threat of New Entrants
6.4.4 Threat of Substitutes
6.4.5 Degree of Rivalry
6.5 Key Demand Indicators
6.6 Key Price Indicators
6.7 Industry Events, Initiatives, and Trends
6.8 Value Chain Analysis
7 Global mRNA Vaccines and Therapeutics Market Segmentation (2017-2032)
7.1 Global mRNA Vaccines and Therapeutics Market (2017-2032) by Product
7.1.1 Market Overview
7.1.2 Vaccines
7.1.2.1 Self-amplifying mRNA-Based Vaccines
7.1.2.2 Conventional Non-amplifying mRNA-Based Vaccines
7.1.3 Drugs
7.2 Global mRNA Vaccines and Therapeutics Market (2017-2032) by Application
7.2.1 Market Overview
7.2.2 Cancer
7.2.3 Infectious Disease
7.2.4 Rare Genetic Disease
7.2.5 Respiratory Disease
7.2.6 Others
7.3 Global mRNA Vaccines and Therapeutics Market (2017-2032) by Treatment Type
7.3.1 Market Overview
7.3.2 Gene Therapy
7.3.3 Cell Therapy
7.3.4 Monoclonal Antibody
7.3.5 Others
7.4 Global mRNA Vaccines and Therapeutics Market (2017-2032) by End User
7.4.1 Market Overview
7.4.2 Hospitals and Clinics
7.4.3 Research & Development Organizations
7.4.4 Others
7.5 Global mRNA Vaccines and Therapeutics Market (2017-2032) by Region
7.5.1 Market Overview
7.5.2 North America
7.5.3 Europe
7.5.4 Asia Pacific
7.5.5 Latin America
7.5.6 Middle East and Africa
8 North America mRNA Vaccines and Therapeutics Market (2017-2032)
8.1 North America mRNA Vaccines and Therapeutics Market (2017-2032) by Product
8.1.1 Market Overview
8.1.2 Vaccines
8.1.2.1 Self-amplifying mRNA-Based Vaccines
8.1.2.2 Conventional Non-amplifying mRNA-Based Vaccines
8.1.3 Drugs
8.2 North America mRNA Vaccines and Therapeutics Market (2017-2032) by Application
8.2.1 Market Overview
8.2.2 Cancer
8.2.3 Infectious Disease
8.2.4 Rare Genetic Disease
8.2.5 Respiratory Disease
8.2.6 Others
8.3 North America mRNA Vaccines and Therapeutics Market (2017-2032) by End User
8.3.1 Market Overview
8.3.2 Hospitals and Clinics
8.3.3 Research & Development Organizations
8.3.4 Others
8.4 North America mRNA Vaccines and Therapeutics Market (2017-2032) by Country
8.4.1 United States
8.4.2 Canada
9 Europe mRNA Vaccines and Therapeutics Market (2017-2032)
9.1 Europe mRNA Vaccines and Therapeutics Market (2017-2032) by Product
9.1.1 Market Overview
9.1.2 Vaccines
9.1.2.1 Self-amplifying mRNA-Based Vaccines
9.1.2.2 Conventional Non-amplifying mRNA-Based Vaccines
9.1.3 Drugs
9.2 Europe mRNA Vaccines and Therapeutics Market (2017-2032) by Application
9.2.1 Market Overview
9.2.2 Cancer
9.2.3 Infectious Disease
9.2.4 Rare Genetic Disease
9.2.5 Respiratory Disease
9.2.6 Others
9.3 Europe mRNA Vaccines and Therapeutics Market (2017-2032) by End User
9.3.1 Market Overview
9.3.2 Hospitals and Clinics
9.3.3 Research & Development Organizations
9.3.4 Others
9.4 Europe mRNA Vaccines and Therapeutics Market (2017-2032) by Country
9.4.1 United Kingdom
9.4.2 Germany
9.4.3 France
9.4.4 Italy
9.4.5 Others
10 Asia Pacific mRNA Vaccines and Therapeutics Market (2017-2032)
10.1 Asia Pacific mRNA Vaccines and Therapeutics Market (2017-2032) by Product
10.1.1 Market Overview
10.1.2 Vaccines
10.1.2.1 Self-amplifying mRNA-Based Vaccines
10.1.2.2 Conventional Non-amplifying mRNA-Based Vaccines
10.1.3 Drugs
10.2 Asia Pacific mRNA Vaccines and Therapeutics Market (2017-2032) by Application
10.2.1 Market Overview
10.2.2 Cancer
10.2.3 Infectious Disease
10.2.4 Rare Genetic Disease
10.2.5 Respiratory Disease
10.2.6 Others
10.3 Asia Pacific mRNA Vaccines and Therapeutics Market (2017-2032) by End User
10.3.1 Market Overview
10.3.2 Hospitals and Clinics
10.3.3 Research & Development Organizations
10.3.4 Others
10.4 Asia Pacific mRNA Vaccines and Therapeutics Market (2017-2032) by Country
10.4.1 China
10.4.2 Japan
10.4.3 India
10.4.4 ASEAN
10.4.5 Australia
10.4.6 Others
11 Latin America mRNA Vaccines and Therapeutics Market (2017-2032)
11.1 Latin America mRNA Vaccines and Therapeutics Market (2017-2032) by Product
11.1.1 Market Overview
11.1.2 Vaccines
11.1.2.1 Self-amplifying mRNA-Based Vaccines
11.1.2.2 Conventional Non-amplifying mRNA-Based Vaccines
11.1.3 Drugs
11.2 Latin America mRNA Vaccines and Therapeutics Market (2017-2032) by Application
11.2.1 Market Overview
11.2.2 Cancer
11.2.3 Infectious Disease
11.2.4 Rare Genetic Disease
11.2.5 Respiratory Disease
11.2.6 Others
11.3 Latin America mRNA Vaccines and Therapeutics Market (2017-2032) by End User
11.3.1 Market Overview
11.3.2 Hospitals and Clinics
11.3.3 Research & Development Organizations
11.3.4 Others
11.4 Latin America mRNA Vaccines and Therapeutics Market (2017-2032) by Country
11.4.1 Brazil
11.4.2 Argentina
11.4.3 Mexico
11.4.4 Others
12 Middle East and Africa mRNA Vaccines and Therapeutics Market (2017-2032)
12.1 Middle East and Africa mRNA Vaccines and Therapeutics Market (2017-2032) by Product
12.1.1 Market Overview
12.1.2 Vaccines
12.1.2.1 Self-amplifying mRNA-Based Vaccines
12.1.2.2 Conventional Non-amplifying mRNA-Based Vaccines
12.1.3 Drugs
12.2 Middle East and Africa mRNA Vaccines and Therapeutics Market (2017-2032) by Application
12.2.1 Market Overview
12.2.2 Cancer
12.2.3 Infectious Disease
12.2.4 Rare Genetic Disease
12.2.5 Respiratory Disease
12.2.6 Others
12.3 Middle East and Africa mRNA Vaccines and Therapeutics Market (2017-2032) by End User
12.3.1 Market Overview
12.3.2 Hospitals and Clinics
12.3.3 Research & Development Organizations
12.3.4 Others
12.4 Middle East and Africa mRNA Vaccines and Therapeutics Market (2017-2032) by Country
12.4.1 Saudi Arabia
12.4.2 United Arab Emirates
12.4.3 Nigeria
12.4.4 South Africa
12.4.5 Others
13 Regulatory Framework
13.1 Regulatory Overview
13.2 US FDA
13.3 EU EMA
13.4 INDIA CDSCO
13.5 JAPAN PMDA
13.6 Others
14 Patent Analysis
14.1 Analysis by Type of Patent
14.2 Analysis by Publication Year
14.3 Analysis by Issuing Authority
14.4 Analysis by Patent Age
14.5 Analysis by CPC Analysis
14.6 Analysis by Patent Valuation
14.7 Analysis by Key Players
15 Grants Analysis
15.1 Analysis by Year
15.2 Analysis by Amount Awarded
15.3 Analysis by Issuing Authority
15.4 Analysis by Grant Application
15.5 Analysis by Funding Institute
15.6 Analysis by Departments
15.7 Analysis by Recipient Organization
16 Funding and Investment Analysis
16.1 Analysis by Funding Instances
16.2 Analysis by Type of Funding
16.3 Analysis by Funding Amount
16.4 Analysis by Leading Players
16.5 Analysis by Leading Investors
16.6 Analysis by Geography
17 Clinical Trials Analysis
17.1 Analysis by Trial Registration Year
17.2 Analysis by Trial Status
17.3 Analysis by Trial Phase
17.4 Analysis by Therapeutic Area
17.5 Analysis by Geography
18 Strategic Initiatives
18.1 Analysis by Partnership Instances
18.2 Analysis by Type of Partnership and Collaborations
18.3 Analysis by Joint Ventures
18.4 Analysis by Leading Players
18.5 Analysis by Geography
19 Supplier Landscape
19.1 Market Share by Top-5 Companies
19.1.1 Market Share Analysis: Global
19.1.2 Market Share Analysis: North America
19.1.3 Market Share Analysis: Europe
19.1.4 Market Share Analysis: Asia Pacific
19.1.5 Market Share Analysis: Others
19.2 Astrazeneca
19.2.1 Financial Analysis
19.2.2 Product Portfolio
19.2.3 Demographic Reach and Achievements
19.2.4 Mergers and Acquisitions
19.2.5 Certifications
19.3 Pfizer, Inc.
19.3.1 Financial Analysis
19.3.2 Product Portfolio
19.3.3 Demographic Reach and Achievements
19.3.4 Mergers and Acquisitions
19.3.5 Certifications
19.4 Sangamo Therapeutics
19.4.1 Financial Analysis
19.4.2 Product Portfolio
19.4.3 Demographic Reach and Achievements
19.4.4 Mergers and Acquisitions
19.4.5 Certifications
19.5 Moderna, Inc.
19.5.1 Financial Analysis
19.5.2 Product Portfolio
19.5.3 Demographic Reach and Achievements
19.5.4 Mergers and Acquisitions
19.5.5 Certifications
19.6 Sanofi
19.6.1 Financial Analysis
19.6.2 Product Portfolio
19.6.3 Demographic Reach and Achievements
19.6.4 Mergers and Acquisitions
19.6.5 Certifications
19.7 Argos Therapeutics
19.7.1 Financial Analysis
19.7.2 Product Portfolio
19.7.3 Demographic
19.7.4 Mergers and Acquisitions
19.7.5 Certifications
19.8 GlaxoSmithKline plc.
19.8.1 Financial Analysis
19.8.2 Product Portfolio
19.8.3 Demographic Reach and Achievements
19.8.4 Mergers and Acquisitions
19.8.5 Certifications
19.9 Gennova Biopharmaceuticals Limited
19.9.1 Financial Analysis
19.9.2 Product Portfolio
19.9.3 Demographic Reach and Achievements
19.9.4 Mergers and Acquisitions
19.9.5 Certifications
19.10 DAIICHI SANKYO COMPANY, LIMITED.
19.10.1 Financial Analysis
19.10.2 Product Portfolio
19.10.3 Demographic Reach and Achievements
19.10.4 Mergers and Acquisitions
19.10.5 Certifications
19.11 Boehringer Ingelheim International GmbH
19.11.1 Financial Analysis
19.11.2 Product Portfolio
19.11.3 Demographic Reach and Achievements
19.11.4 Mergers and Acquisitions
19.11.5 Certifications
20 Global mRNA Vaccines and Therapeutics Market – Distribution Model (Additional Insight)
20.1 Overview
20.2 Potential Distributors
20.3 Key Parameters for Distribution Partner Assessment
21 Key Opinion Leaders (KOL) Insights (Additional Insight)
*Additional insights provided are customisable as per client requirements.
* The coverage of the Market Landscape section depends on the data availability and may cover a minimum of 80% of the total market. The EMR team strives to make this section as comprehensive as possible.
**The supplier list is not exhaustive. Moreover, we can provide analysis of companies as per custom requests.
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