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The ischemic heart disease drugs market was valued at USD 4.94 billion in 2023, driven by the rising incidence of heart diseases across the globe. The market is expected to grow at a CAGR of 4.35% during the forecast period of 2024-2032, with the values likely to attain USD 6.87 billion by 2032.
Ischemic heart diseases are medical conditions under which the patient’s heart arteries that supply blood to the heart muscle get narrowed, lowering the blood flow. In severe cases, the patient suffers from artery blockage which is then treated surgically (if feasible). To improve the blood flow in such medical conditions, ischemic heart disease drugs are prescribed to patients. The market is expected to witness substantial growth due to the increasing prevalence of heart diseases worldwide. With the increasing prevalence, the increasing demand for ischemic heart disease drugs is corresponding.
Prevalence of Heart Diseases Boosting the Market Demand
The increasing prevalence of cardiovascular diseases is contributing to the increased demand for ischemic heart disease drugs. According to the new Global Burden of Disease (GBD) special report published in 2023, ischemic heart disease is the leading cause of death for cardiovascular disease worldwide. It causes 108.8 deaths per 100,000 people. Estimated by the Centers for Disease Control and Prevention nearly 805,000 people suffer from a heart attack every year in the United States. As a result, the demand for effective therapeutics is on the rise.
Rising Approvals by the Regulatory Authorities to Meet the Ischemic Heart Disease Drugs Market Demand
In March 2024, the U.S. Food and Drug Administration gave clearance to Wegovy (semaglutide) injection, expanding its use to reduce the risk of cardiovascular death, heart attack, and stroke in overweight or obese adults. This approval marks a significant advancement in the management of ischemic heart disease, particularly for patients at higher risk due to their weight. Wegovy is an established medication for weight management that is now additionally useful in the treatment of obesity with direct cardiovascular benefits, potentially transforming the therapeutic landscape for ischemic heart disease. The approval was based on a robust, multi-national, placebo-controlled double-blind trial involving over 17,600 participants, reinforcing the drug's efficacy and safety. This development is expected to drive increased adoption of Wegovy in cardiovascular risk management, leading to increased market penetration and potentially stimulating further research and development in cardio-metabolic drugs. Consequently, the ischemic heart disease drugs market is likely to witness significant growth, with enhanced treatment options that address both the symptoms of heart disease and risk factors such as obesity.
In December 2023, the FDA approved colchicine drug (traditionally used for gout and other inflammatory conditions) for the prevention of heart disease as well. Previously Lodoco, colchicine was approved recently to manage cholesterol levels, and blood pressure and reduce the risk of heart disease and stroke. This approval marked a significant expansion in the use of colchicine, positioning it as a potential drug in ischemic heart disease management. This approval could potentially trigger increased clinical research and investment for the repurposing of other existing drugs for cardiovascular indications, boosting the market growth.
Regulatory Authorities Expanding the Application of Drug
In March 2024, Regeneron Pharmaceuticals, Inc. announced that the U.S. Food & Drug Administration (FDA) has approved the expansion of Praluent® (alirocumab) usage to include pediatric patients aged 8 and older with heterozygous familial hypercholesterolemia (HeFH). This approval marks a significant expansion in the treatment landscape for ischemic heart disease, as Praluent, targeting the PCSK9 enzyme, becomes one of the few therapies available to younger patients at high genetic risk of heart disease. With the expanded usage of Praluent, it will now be helpful in treating heart disease in early diagnosis and effectively managing the condition in the long term. Consequently, the market is poised for substantial growth.
Key Trend | Impact |
Increasing Prevalence of Cardiovascular Diseases | The market is witnessing a growing geriatric population, susceptible to ischemic heart diseases. The increasing geriatric population is contributing to the increasing prevalence of the ischemic heart disease IHD worldwide. |
Advancements in Drug Development | With increasing advancements in drug development, the market is witnessing a significant shift towards personalised medicine in the treatment of IHD. |
Advent of Biologics and Novel Drugs Molecules | The market is experiencing a significant shift towards the development of biologics and novel small-molecule drugs offering innovative treatments. |
Increasing Emphasis on Early Prevention | Increasing demand for medication that curbs or manages the occurrence of risk factors leading to IHDs is driving the market growth. The demand for blood pressure and cholesterol management drugs is consistent. |
Market Breakup by Disease Type
Market Breakup by Drug Class
Market Breakup by Distribution Channel
Market Breakup by Region
Angina Pectoris Leads the Market Segmentation Based on Disease Type
The market share based on disease type includes angina pectoris and myocardial infarction. The angina pectoris segment is expected to lead the market due to its high prevalence. Angina is a symptom of coronary artery disease in which chest pain is experienced by the patient due to reduced blood flow to the heart muscles. Frequent encounters drive demand for drugs to provide relief and improve patient’s quality of life.
Market Segmentation Based on Drug Class to Witness Substantial Growth
The drug class segmentation includes anti-dyslipidemic drugs, calcium channel blockers, beta-blockers, ACE inhibitors, ARBs, vasodilators, and antithrombotic agents. The drug class segmentation is dominated by anti-dyslipidemic drugs as management of blood lipid levels is necessary to avoid and treat ischemic heart diseases (IHD). These drugs include statins, fibrates, and cholesterol absorption inhibitors that are considered effective in reducing cholesterol levels. It is particularly effective in managing bad cholesterol LDL, a major risk factor for the formation of plaques in the arteries.
Based on the regions, the market report covers the United States, EU-4 (Germany, France, Italy, Spain) and the United Kingdom, Japan and India, with each region contributing to the overall dynamics of the market. United States is leading the market share with the presence of a robust healthcare infrastructure to provide high-end treatments to patients. The increasing prevalence of people suffering from heart diseases such as coronary artery disease (CAD), arrhythmias, cardiomyopathy, and valvular heart diseases, among others is collectively driving the demand for ischemic heart disease drugs in the region. Data from the Centers for Disease Control and Prevention states that in the United States, every 33 seconds cardiovascular disease claims a human life. The annual expenditure on heart disease amounted to USD 239.9 billion from 2018 to 2019.
The key features of the market report include patent analysis, clinical trials analysis, grants, funding and investment analysis, and strategic initiatives by the leading players. The major companies in the market are as follows:
Eli Lilly and Company
Eli Lilly and Company was established in 1876 and is currently headquartered in Indianapolis, Indiana, USA. The company is focused on developing and distributing effective medications for various including endocrinology, oncology, immunology, neuroscience, and cardiovascular diseases.
Bayer AG
Founded in 1863, Bayer AG is a prominent pharmaceutical company focused on cardiology, hematology and oncology related prescription drugs. Some notable products in the cardiovascular domain include aspirin, Xarelto (rivaroxaban), and Eylea (aflibercept) among others.
Pfizer Inc.
Headquartered in New York, USA, this company was established in 1849. The company has a strong product portfolio of cardiovascular diseases as well as continuously takes part in research initiatives for providing a diverse range of medications to consumers.
Other players in the market include Sanofi, Novartis AG, Baxter International, Inc., Merck & Co., Inc., Johnson & JohnsonServices, Inc., Amgen Inc., Boehringer Ingelheim International GmbH
F. Hoffmann-La Roche AG, GlaxoSmithKline plc, Bristol-Myers Squibb Company, and Eisai Co., Ltd.
Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.
REPORT FEATURES | DETAILS |
Base Year | 2023 |
Historical Period | 2017-2023 |
Forecast Period | 2024-2032 |
Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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Breakup by Disease |
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Breakup by Drug Class |
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Breakup by Distribution Channel |
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Breakup by Region |
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Market Dynamics |
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Supplier Landscape |
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Companies Covered |
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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.
1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage – Key Segmentation and Scope
1.4 Research Methodology
2 Executive Summary
3 Ischemic Heart Disease Drugs Market Overview: 8 Major Market
3.1 Ischemic Heart Disease Drugs Market Historical Value (2017-2023)
3.2 Ischemic Heart Disease Drugs Market Forecast Value (2024-2032)
4 Vendor Positioning Analysis
4.1 Key Vendors
4.2 Prospective Leaders
4.3 Niche Leaders
4.4 Disruptors
5 Ischemic Heart: Disease Drugs Overview
5.1 Guidelines and Stages
5.2 Pathophysiology
5.3 Screening and Diagnosis
5.4 Therapy Pathway
6 Patient Profile
6.1 Patient Profile Overview
6.2 Patient Psychology and Emotional Impact Factors
6.3 Risk Assessment and Therapy Success Rate
7 Ischemic Heart Disease Market Epidemiology Scenario and Forecast – 8 Major Markets
7.1 8MM Epidemiology Scenario Overview (2017-2032)
7.1.1 Prevalence, by Country
7.1.1.1 U.S.
7.1.1.2 U.K.
7.1.1.3 EU4
7.1.1.4 India
7.1.1.5 Japan
7.1.2 Mortality by Country
7.1.2.1 U.S.
7.1.2.2 U.K.
7.1.2.3 EU4
7.1.2.4 India
7.1.2.5 Japan
7.1.3 Treatment Seeking Rate by Country
7.1.3.1 U.S.
7.1.3.2 U.K.
7.1.3.3 EU4
7.1.3.4 India
7.1.3.5 Japan
8 Ischemic Heart Disease Drugs Market Landscape: 8 Major Market*
8.1 Ischemic Heart Disease Drugs Market: Developers Landscape
8.1.1 Analysis by Year of Establishment
8.1.2 Analysis by Company Size
8.1.3 Analysis by Region
8.2 Ischemic Heart Disease Drugs Market: Product Landscape
8.2.1 Analysis by Disease
8.2.2 Analysis by Drug Class
9 Ischemic Heart Disease Drugs Market Therapy Challenges and Unmet Needs
9.1 Therapy Pathway Challenges
9.2 Compliance and Drop-Out Analysis
9.3 Awareness and Prevention Gaps
10 Cost of Therapy
11 Ischemic Heart Disease Drugs: Market Dynamics
11.1 Market Drivers and Constraints
11.2 SWOT Analysis
11.2.1 Strengths
11.2.2 Weaknesses
11.2.3 Opportunities
11.2.4 Threats
11.3 PESTEL Analysis
11.3.1 Political
11.3.2 Economic
11.3.3 Social
11.3.4 Technological
11.3.5 Legal
11.3.6 Environment
11.4 Porter’s Five Forces Model
11.4.1 Bargaining Power of Suppliers
11.4.2 Bargaining Power of Buyers
11.4.3 Threat of New Entrants
11.4.4 Threat of Substitutes
11.4.5 Degree of Rivalry
11.5 Key Demand Indicators
11.6 Key Price Indicators
11.7 Industry Events, Initiatives, and Trends
11.8 Value Chain Analysis
12 Ischemic Heart Disease Drugs Market Segmentation: 8 Major Market
12.1 Ischemic Heart Disease Drugs Market (2017-2032) by Disease
12.1.1 Market Overview
12.1.2 Angina Pectoris
12.1.3 Myocardial Infarction
12.2 Ischemic Heart Disease Drugs Market (2017-2032) by Drug Class
12.2.1 Market Overview
12.2.2 Anti-Dyslipidemic Drugs
12.2.3 Calcium Channel Blockers
12.2.4 Beta-Blockers
12.2.5 ACE Inhibitors
12.2.6 ARBs
12.2.7 Vasodilators
12.2.8 Antithrombotic Agents
12.3 Ischemic Heart Disease Drugs Market by Distribution Channel
12.3.1 Market Overview
12.3.2 Hospital Pharmacy
12.3.3 Retail Pharmacy
12.3.4 Online Pharmacy
12.4 Ischemic Heart Disease Drugs Market by Region
12.4.1 Market Overview
12.4.2 United States
12.4.3 EU-4 and the United Kingdom
12.4.3.1 Germany
12.4.3.2 France
12.4.3.3 Italy
12.4.3.4 Spain
12.4.3.5 United Kingdom
12.4.4 Japan
12.4.5 India
13 United States Ischemic Heart Disease Drugs Market (2017-2032)
13.1 United States Ischemic Heart Disease Drugs Market Historical Value (2017-2023)
13.2 United States Ischemic Heart Disease Drugs Market Forecast Value (2024-2032)
13.3 United States Ischemic Heart Disease Drugs Market (2017-2032) by Disease
13.3.1 Market Overview
13.3.2 Angina Pectoris
13.3.3 Myocardial Infarction
13.4 United States Ischemic Heart Disease Drugs Market (2017-2032) by Drug Class
13.4.1 Market Overview
13.4.2 Anti-Dyslipidemic Drugs
13.4.3 Calcium Channel Blockers
13.4.4 Beta-Blockers
13.4.5 ACE Inhibitors
13.4.6 ARBs
13.4.7 Vasodilators
13.4.8 Antithrombotic Agents
14 EU-4 and United Kingdom Ischemic Heart Disease Drugs Market (2017-2032)
14.1 EU-4 and United Kingdom Ischemic Heart Disease Drugs Market Historical Value (2017-2023)
14.2 EU-4 and United Kingdom Ischemic Heart Disease Drugs Market Forecast Value (2024-2032)
14.3 EU-4 and United Kingdom Ischemic Heart Disease Drugs Market (2017-2032) by Disease
14.3.1 Market Overview
14.3.2 Angina Pectoris
14.3.3 Myocardial Infarction
14.4 EU-4 and United Kingdom Ischemic Heart Disease Drugs Market (2017-2032) by Drug Class
14.4.1 Market Overview
14.4.2 Anti-Dyslipidemic Drugs
14.4.3 Calcium Channel Blockers
14.4.4 Beta-Blockers
14.4.5 ACE Inhibitors
14.4.6 ARBs
14.4.7 Vasodilators
14.4.8 Antithrombotic Agents
15 Japan Ischemic Heart Disease Drugs Drugs Market
15.1 Japan Ischemic Heart Disease Drugs Market Historical Value (2017-2023)
15.2 Japan Ischemic Heart Disease Drugs Market Forecast Value (2024-2032)
15.3 Japan Ischemic Heart Disease Drugs Market (2017-2032) by Disease
15.3.1 Market Overview
15.3.2 Angina Pectoris
15.3.3 Myocardial Infarction
15.4 Japan Ischemic Heart Disease Drugs Market (2017-2032) by Drug Class
15.4.1 Market Overview
15.4.2 Anti-Dyslipidemic Drugs
15.4.3 Calcium Channel Blockers
15.4.4 Beta-Blockers
15.4.5 ACE Inhibitors
15.4.6 ARBs
15.4.7 Vasodilators
15.4.8 Antithrombotic Agents
16 India Ischemic Heart Disease Drugs Drugs Market
16.1 India Ischemic Heart Disease Drugs Market (2017-2032) Historical Value (2017-2023)
16.2 India Ischemic Heart Disease Drugs Market (2017-2032) Forecast Value (2024-2032)
16.3 India Ischemic Heart Disease Drugs Market (2017-2032) by Disease
16.3.1 Market Overview
16.3.2 Angina Pectoris
16.3.3 Myocardial Infarction
16.4 India Ischemic Heart Disease Drugs Market (2017-2032) by Drug Class
16.4.1 Market Overview
16.4.2 Anti-Dyslipidemic Drugs
16.4.3 Calcium Channel Blockers
16.4.4 Beta-Blockers
16.4.5 ACE Inhibitors
16.4.6 ARBs
16.4.7 Vasodilators
16.4.8 Antithrombotic Agents
17 Regulatory Framework
17.1 Regulatory Overview
17.2 US FDA
17.3 EU EMA
17.4 INDIA CDSCO
17.5 JAPAN PMDA
17.6 Others
18 Patent Analysis
18.1 Analysis by Type of Patent
18.2 Analysis by Publication Year
18.3 Analysis by Issuing Authority
18.4 Analysis by Patent Age
18.5 Analysis by CPC Analysis
18.6 Analysis by Patent Valuation
18.7 Analysis by Key Players
19 Clinical Trial Analysis
19.1 Analysis by Trial Registration Year
19.2 Analysis by Trial Status
19.3 Analysis by Trial Phase
19.4 Analysis by Therapeutic Area
19.5 Analysis by Geography
20 Grant Analysis
20.1 Analysis by Year
20.2 Analysis by Amount Awarded
20.3 Analysis by Issuing Authority
20.4 Analysis by Grant Product
20.5 Analysis by Funding Institute
20.6 Analysis by Departments
20.7 Analysis by Recipient Organization
21 Funding and Investment Analysis
21.1 Analysis by Funding Instances
21.2 Analysis by Type of Funding
21.3 Analysis by Funding Amount
21.4 Analysis by Leading Players
21.5 Analysis by Leading Investors
21.6 Analysis by Geography
22 Strategic Initiatives
22.1 Analysis by Partnership Instances
22.2 Analysis by Type of Partnership
22.3 Analysis by Leading Players
22.4 Analysis by Geography
23 Supplier Landscape
23.1 Market Share by Top 5 Companies
23.2 Eli Lilly and Company
23.2.1 Financial Analysis
23.2.2 Product Portfolio
23.2.3 Demographic Reach and Achievements
23.2.4 Mergers and Acquisitions
23.2.5 Certifications
23.3 Bayer AG
23.3.1 Financial Analysis
23.3.2 Product Portfolio
23.3.3 Demographic Reach and Achievements
23.3.4 Mergers and Acquisitions
23.3.5 Certifications
23.4 Pfizer, Inc.
23.4.1 Financial Analysis
23.4.2 Product Portfolio
23.4.3 Demographic Reach and Achievements
23.4.4 Mergers and Acquisitions
23.4.5 Certifications
23.5 Sanofi S.A.
23.5.1 Financial Analysis
23.5.2 Product Portfolio
23.5.3 Demographic Reach and Achievements
23.5.4 Mergers and Acquisitions
23.5.5 Certifications
23.6 Novartis AG
23.6.1 Financial Analysis
23.6.2 Product Portfolio
23.6.3 Demographic Reach and Achievements
23.6.4 Mergers and Acquisitions
23.6.5 Certifications
23.7 Baxter International, Inc.
23.7.1 Financial Analysis
23.7.2 Product Portfolio
23.7.3 Demographic Reach and Achievements
23.7.4 Mergers and Acquisitions
23.7.5 Certifications
23.8 Merck & Co., Inc.
23.8.1 Financial Analysis
23.8.2 Product Portfolio
23.8.3 Demographic Reach and Achievements
23.8.4 Mergers and Acquisitions
23.8.5 Certifications
23.9 Johnson & Johnson Services, Inc.
23.9.1 Financial Analysis
23.9.2 Product Portfolio
23.9.3 Demographic Reach and Achievements
23.9.4 Mergers and Acquisitions
23.9.5 Certifications
23.10 Amgen Inc.
23.10.1 Financial Analysis
23.10.2 Product Portfolio
23.10.3 Demographic
23.10.4 Mergers and Acquisitions
23.10.5 Certifications
23.11 Boehringer Ingelheim International GmbH
23.11.1 Financial Analysis
23.11.2 Product Portfolio
23.11.3 Demographic Reach and Achievements
23.11.4 Mergers and Acquisitions
23.11.5 Certifications
23.12 F. Hoffmann-La Roche AG
23.12.1 Financial Analysis
23.12.2 Product Portfolio
23.12.3 Demographic Reach and Achievements
23.12.4 Mergers and Acquisitions
23.12.5 Certifications
23.13 GlaxoSmithKline plc
23.13.1 Financial Analysis
23.13.2 Product Portfolio
23.13.3 Demographic Reach and Achievements
23.13.4 Mergers and Acquisitions
23.13.5 Certifications
23.14 Bristol-Myers Squibb Company
23.14.1 Financial Analysis
23.14.2 Product Portfolio
23.14.3 Demographic Reach and Achievements
23.14.4 Mergers and Acquisitions
23.14.5 Certifications
23.15 Eisai Co., Ltd.
23.15.1 Financial Analysis
23.15.2 Product Portfolio
23.15.3 Demographic Reach and Achievements
23.15.4 Mergers and Acquisitions
23.15.5 Certifications
24 Ischemic Heart Disease Drugs Market – Distribution Model (Additional Insight)
24.1 Overview
24.2 Potential Distributors
24.3 Key Parameters for Distribution Partner Assessment
25 Key Opinion Leaders (KOL) Insights (Additional Insight)
*Additional insights provided are customisable as per client requirements.
* The coverage of the Market Landscape section depends on the data availability and may cover a minimum of 80% of the total market. The EMR team strives to make this section as comprehensive as possible.
**The supplier list is not exhaustive. Moreover, we can provide analysis of companies as per custom requests.
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