Global In-Vitro Colorectal Cancer Screening Tests Market Report and Forecast 2025-2034

Global In-Vitro Colorectal Cancer Screening Tests Market Outlook

The global in-vitro colorectal cancer screening tests market size was valued at USD 920.4 million in 2024, driven by the rising prevalence of colorectal cancer across 8 major markets. The market is expected to grow at a CAGR of 5.53% during the forecast period of 2025-2034, with the values likely to rise from USD 970.2 million in 2025 to USD 1492.8 million by 2034.

Global In-Vitro Colorectal Cancer Screening Tests Market Overview

Colorectal cancer (CRC) accounts for 10% of all cancer cases. Ranking as the third most common type of cancer, it is estimated that 3.2 million new colorectal cancer cases per year will arise by 2040. Early detection of the cancer is essential for the successful treatment of the disease. With the rising prevalence of colorectal cancer fuelling the demand for efficient and accurate diagnostic methods, the in-vitro colorectal cancer screening tests market demand is anticipated to experience a surge in the coming years.

Metastatic colorectal cancer is accountable for about 90% of the cancer fatalities. To facilitate early detection of cancer metastasis, scientists have deployed machine learning and artificial intelligence associated tools in diagnostic techniques. In November 2023, scientists investigated 11 biomarkers associated with metastatic CRC using a machine learning (ML) approach. Out of 11 biomarkers, 4 gained experimental validation, indicating the potential of machine learning in biomarker discovery. The integration of algorithms such as LASSO and P-SVM, helped in improving efficiency and accuracy of biomarker selection process.

In-vitro colorectal cancer screening tests market growth is also driven by intensive research initiatives aimed at improving colorectal cancer screening effectiveness and accessibility. These developments will positively impact early detection rates and improve patients, thereby propelling the demand for in-vitro colorectal cancer screening tests.

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Purchase the Regional Overview for USD 1099

If you choose to purchase the full report at a later stage, the amount already paid will be adjusted, and you will only need to pay the remaining balance.

Purchase the Regional Overview for USD 1099

If you choose to purchase the full report at a later stage, the amount already paid will be adjusted, and you will only need to pay the remaining balance.

Purchase the Regional Overview for USD 1099

If you choose to purchase the full report at a later stage, the amount already paid will be adjusted, and you will only need to pay the remaining balance.

Global In-Vitro Colorectal Screening Tests Market Trends

Global In-Vitro Colorectal Cancer Screening Tests Market Segmentation

Market Breakup by Test Type

• Fecal Occult Blood Test (FOBT) 
  • Guaiac FOBT 
  • Immuno-FOBT (FIT)

• Stool DNA Test (sDNA)

• Colonoscopy

• Flexible Sigmoidoscopy

• CT Colonography (Virtual Colonoscopy)

• Biomarker Tests 
  • CEA Tests 
  • Other Blood-Based Tests

The market segmentation by test type includes fecal occult blood test (FOBT) which can be further segmented into guaiac and mmune variations. Stool DNA test (sDNA), colonoscopy, flexible sigmoidoscopy, CT colonography, and biomarker tests such as CEA and other blood-based tests. These diagnostic tests offer diverse approaches for early detection of colorectal cancer.

Market Breakup by Technology

• Tumor Biomarker-Based Tests

• Guaiac-Based Tests

• Immuno-FOBT (FIT)

• DNA-Based Tests

• Colonoscopy Technology

• Other Emerging Technologies

Based on technology, the market is divided into tumor biomarker-based tests, guaiac-based tests, Immuno-FOBT (FIT), DNA-based tests, and colonoscopy technology, among other emerging technologies. Technological advancements in screening methods are expected to boost the in-vitro colorectal cancer screening tests market size.

Market Breakup by Collection Method

• Guaiac Sampling

• Immuno-FOBT Sampling

• Stool DNA Sampling

• Blood Sampling (for Biomarker Tests)

• Others

The market is segmented by collection method into guaiac sampling, Immuno-FOBT sampling, stool DNA sampling, and blood sampling for biomarker tests, among others. This market segment ensures efficient and accurate sample collection in colorectal cancer screening.

Market Breakup by End User

• Hospitals

• Diagnostic Laboratories

• Ambulatory Surgical Centers

• Research Institutes

• Others

End users of the market encompass hospitals, diagnostic laboratories, ambulatory surgical centers, research institutes, and other facilities. Hospitals and diagnostic laboratories serve as primary centers for screening and diagnosis of colorectal cancer.

Market Breakup by Region

• North America

• Europe

• Asia Pacific

• Latin America

• Middle East and Africa

The market is segmented by region, covering North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. North America is the leading player in the market, which can be attributed to the high incidence rate of colorectal cancer in the region which fuels the demand for screening tests. In addition, the presence of an advanced healthcare system and the rising geriatric population base is poised to support market growth in the region.

Global In-Vitro Colorectal Cancer Screening Tests Market: Competitor Landscape

The key features of the market report include patent analysis, grants analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:

• Abbott Laboratories

• F. Hoffmann-La Roche Ltd.

• Siemens Healthineers AG

• Beckman Coulter, Inc. (a Danaher Company)

• Biohit Oyj

• Epigenomics AG

• Exact Sciences Corporation

• Hemosure, Inc.

• Randox Laboratories Ltd.

• QIAGEN N.V.

• Eiken Chemical Co., Ltd.

• Novigenix SA

• Sysmex Corporation

• Immundiagnostik AG

• Epi proColon (Epigenomics AG)

Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.

Key Highlights of the Report

Key Queries Solved in the Global In-Vitro Colorectal Cancer Screening Tests Market Report

• How is the market landscape expected to evolve in upcoming years?
• What are the major market trends influencing the market? 
• What are the major drivers, opportunities, and restraints in the market? 
• What will be the effect of each driver, challenge, and opportunity on the market? 
• Which country is poised to lead the market share in the forecast period? 
• Which country is expected to experience expedited growth during the forecast period? 
• What technology type will dominate the in-vitro colorectal cancer screening tests market share? 
• What type of collection methods are expected to dominate the respective market segment? 
• Which applications are expected to significantly impact the growth of the market?
• Which test type in the market is expected to achieve high demand in the coming years?
• What are the key research initiatives expected to boost the market value during the forecast period? 
• Which segment has the highest impact on the market size? 
• How are partnerships, collaborations, and mergers & acquisitions shaping the market dynamics?