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Report Overview

2023

Base Year

2017-2023

Historical Year

2024-2032

Forecast Year

Global Gene Expression Market Outlook

The global gene expression market size was valued at USD 13.3 billion in 2023, driven by advancements in gene expression analysis across the globe. The market is expected to grow at a CAGR of 10.42% during the forecast period of 2024-2032, with the values likely to rise from USD 14.7 billion in 2024 to USD 32.4 billion by 2032.

Key Takeaways

  • Expanding applications of next-generation technology including oncology studies, biomarker discovery, and personalized therapeutics are likely to augment market demand.
  • It is estimated that 35 million new cancer cases will arise by 2050.  The rising inclination of patients towards precision oncology will positively influence the market dynamics.
  • Cost reductions of DNA sequencing has played a significant role in making gene expression more accessible and affordable. In June 2023, Illumina Inc. announced that technological advancements helped the company lower its cost of human genome sequencing (from USD 150,000 to USD 200).

The gene expression market growth is driven by the rapid advancements in the field of genomics. In pharmaceutical companies, gene expression analysis is increasingly employed for drug discovery and development to accommodate the clinical needs of the growing patient population. On the other hand, biotechnology companies are actively investing in the market to develop novel therapies. Additionally, the rising prevalence of chronic diseases such as cancer and the substantial funding for genomic research is expected to accelerate the market growth in the forecast period.

Global Gene Expression Market Trends and Developments

Growing preference for personalized medicine, rising demand for precision oncology, expansion of RNA sequencing applications, and increasing use of gene expression research in infectious disease research comprise some of the key trends and developments in the market.

Date Company Event
August 2023 Almac Group Almac Diagnostic Services (a member of the contract development and manufacturing organization Almac Group) expanded its NGS portfolio of DNA sequencing service offerings by investing in Illumina NovaSeq X Plus in its Ireland facility.
July 2023 Neoleukin Therapeutics, Inc. Neoleukin Therapeutics, Inc., entered into a merger agreement with Neurogene Inc., a biotechnology company focused on the development of genetic medicines for rare neurological diseases. The merger is expected to strengthen the genetic drug pipeline of Neurogene Inc. and develop medications for rare diseases such as Rett Syndrome. 
March 2023 Illumina Inc. Illumina Inc. launched its first whole genome sequencing (WGS) assay called ‘Illumina Complete Long Read Prep Human’ that has been compatible with multiple sequencing systems. The product  offers both long and short-read sequencing on the NovaSeq platform, along with simplified workflows and reduced DNA input requirements. Early customer data demonstrates high accuracy and flexibility, with the promotional price at USD 1,350 per whole genome.
March 2023 Chroma Medicine Chroma Medicine, Inc., secured USD 135 million in series B financing led by Google Ventures. The firm plans to use the investment to expand its precision genomic medicines portfolio and develop its epigenetic editing technology.


 

Key Trend Impact
Growing Preference for Personalized Medicine Gene expression analysis facilitates understanding of disease mechanisms and helps identify targeted therapies. The growing focus on personalized medicine, in which a specific treatment plan is designed based on the patient’s genetic makeup, is elevating the gene expression market value.
Rising Demand for Precision Oncology Gene expression analysis is increasingly used in oncology to identify molecular signatures of tumors. Thus, the advancement in genomics is fuelling a shift towards more precise and personalized cancer care.
Expansion of RNA Sequencing Applications RNA sequencing (RNA-seq) is expanding beyond basic research into clinical applications, including disease diagnosis, treatment monitoring, and understanding of the immune response.
Increasing Use of Gene Expression in Infectious Disease Research Gene expression profiling finds its application in infectious disease research such as the immune response to infections and identifying potential therapeutic targets for emerging pathogens. With the rising prevalence of infectious diseases and the growing demand for effective therapeutics, the market is expected to witness a surge.

Global Gene Expression Market Demand

The market demand is propelled by the application of gene expression technologies across various domains from basic research to diagnostics and drug discovery. Heightened patient awareness and increased accessibility to healthcare services further bolster the market demand. The rising prevalence of genetic disorders has increased the focus on gene expression studies to identify potential therapeutic targets. With the data suggesting that 72% of rare diseases  have a genetic origin, the gene expression market size is projected to expand in the forecast period.

Technological advancements such as the integration of artificial intelligence (AI) and machine learning in gene expression analysis are anticipated to contribute to market growth. Such innovations will simplify complex data and assist in predicting treatment outcomes, facilitating the utilization of gene expression profiles in clinical decision-making.

Global Gene Expression Market Segmentation

“Global Gene Expression Market Report and Forecast 2024-2032” offers a detailed analysis of the market based on the following segments:

Market Breakup Categories
Products and Services Consumables, Instruments, Services
Technology Polymerase Chain Reaction, Next Generation Sequencing, DNA Microarray, Others
Application Disease Diagnosis, Drug Discovery, Drug Development, Others
End User Pharmaceutical and Biotechnology, Academic and Research Institutes, Diagnostic and Clinical Laboratories, Others
Region North America, Europe, Asia Pacific, Latin America, Middle East, and Africa

By products and services, the market is segmented into consumables, instruments, and services. This market segment caters to different stages of gene expression analysis, research, and experimentation.

In terms of technology, the gene expression market share includes polymerase chain reaction (PCR), next generation sequencing (NGS), DNA microarray, and other emerging techniques. Each technology in the market provides distinct advantages in terms of throughput, sensitivity, and cost-effectiveness.

Gene expression finds its application in disease diagnosis, drug discovery, drug development, and other research and clinical applications. This segment actively works on addressing a wide range of biological questions and medical needs.

End-users of gene expression products and services comprise pharmaceutical and biotechnology companies, academic and research institutes, diagnostic and clinical laboratories, and other organizations involved in life sciences research and healthcare.

Based on region, the market report covers North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. The gene expression market shows regional disparities affected by factors such as technological advancements, regulatory environments, and healthcare expenditure.

Global Gene Expression Market: Competitive Landscape

The key market players are contributing to the gene expression market growth through strategic mergers and acquisitions initiatives, novel product launches, and continuous research and development efforts aimed at providing improved patient solutions.

Company Year Founded Headquarters Products/Services
Illumina Inc 1998 San Diego, California, USA Next-generation sequencing (NGS) systems, reagents, and related products for genetic and genomic analysis
Thermo Fisher Scientific 1956 Waltham, Massachusetts, USA Waltham, Massachusetts, USA    Products and services for research, analysis, discovery, and diagnostics, including gene expression solutions, sequencing, and life science reagents
Promega Corporation 1978 Madison, Wisconsin, USA Reagents and systems for life sciences research, including gene expression analysis kits and assays
F. Hoffmann La Roche Ltd. 1896 Basel, Switzerland Diagnostic and research tools, including systems and reagents for gene expression analysis

Other key players in the market include Revvity Inc., Agilent Technologies Inc., Oxford Nanopore Technologies Inc., PacBio, QIAGEN, Bio-Rad Laboratories Inc., Danaher Life Sciences, and Takara Bio Inc.

Global Gene Expression Market Analysis by Region

In North America, the market is witnessing significant growth which can be attributed to robust research and development efforts aimed at expanding the genomics field. Major funding from the public and private sectors also supports the ongoing gene expression studies. In addition, the presence of a well-established healthcare system and growing demand for targeted therapies is expected to boost the gene expression market size in the forecast period.

Asia Pacific is projected to experience rapid growth in the coming years supported by the rising disposable income and improvement of healthcare facilities. Moreover, the regional market offers lucrative growth opportunities for the key market players due to various factors such as the huge population base, rising prevalence of chronic diseases, and increased expenditure on healthcare services and products.

Key Highlights of the Report

REPORT FEATURES DETAILS
Base Year 2023
Historical Period 2017-2023
Forecast Period 2024-2032
Scope of the Report

Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:

  • Products and Services
  • Technology
  • Application
  • End User
  • Region
Breakup by Products and Services
  • Consumables 
  • Instruments
  • Services
Breakup by Technology
  • Polymerase Chain Reaction 
  • Next Generation Sequencing 
  • DNA Microarray 
  • Others
Breakup by Application
  • Disease Diagnosis 
  • Drug Discovery
  • Drug Development 
  • Others
Breakup by End User
  • Pharmaceutical and Biotechnology Companies
  • Academic and Research Institute
  • Diagnostic and Clinical Laboratories
  • Others
Breakup by Region
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa
Market Dynamics
  • Market Drivers and Constraints
  • SWOT Analysis
  • Porter’s Five Forces Model 
  • Key Demand Indicators
  • Key Price Indicators
  • Industry Events, Initiatives, and Trends 
  • Value Chain Analysis
Supplier Landscape
  • Market Structure
  • Company Profiles
    • Financial Analysis
    • Product Portfolio
    • Demographic Reach and Achievements
    • Mergers and Acquisitions
    • Certifications
Companies Covered
  • Illumina Inc. 
  • Thermo Fisher Scientific 
  • Promega Corporation 
  • Revvity Inc.
  • Agilent Technologies Inc. 
  • Oxford Nanopore Technologies Inc.
  • F. Hoffmann La Roche Ltd.
  • PacBio 
  • QIAGEN 
  • Bio-Rad Laboratories Inc. 
  • Danaher Life Sciences 
  • Takara Bio Inc. 

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Key Questions Answered in the Report

The market attained a value of about USD 13.3 billion in 2023 driven by advancements in gene expression analysis across the globe.

The market is anticipated to grow at a CAGR of 10.4% during the forecast period of 2024-2032, likely to reach a market value of USD 32.4 billion by 2032.

The rising inclination of patients toward personalized medicines is fuelling the demand for the market.

One of the significant market trends is the increased acquisition and merger initiatives by the key market players. In July 2023, Neoleukin Therapeutics, Inc. entered into a merger agreement with Neurogene Inc. to expand their genetic drugs pipeline including NGN-401 for Rett Syndrome.

Based on the products and services, the market is segmented into consumables, instruments, and services.

Based on the technology, the market is segmented into polymerase chain reaction, next generation sequencing, and DNA microarray, among others.

Major end users of the market include pharmaceutical and biotechnology, academic and research institutes, diagnostic and clinical laboratories, among others.

Gene expression is used in disease diagnosis, drug discovery, and development, among others.

The major regions of the market include North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. 

Key players involved in the market are Illumina Inc., Thermo Fisher Scientific, Promega Corporation, Revvity Inc., Agilent Technologies Inc., Oxford Nanopore Technologies Inc., F. Hoffmann La Roche Ltd., PacBio, QIAGEN, Bio-Rad Laboratories Inc., Danaher Life Sciences, and Takara Bio Inc.

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