Global Exosomes Drug Market Report and Forecast 2024-2032

Exosomes Drug Market Outlook

The rising cases of cancer have been driving the value of the global exosomes drug market. The number of cancer cases was close to 23.39 million in 2023. The prevalence of cancer diseases is likely to grow at the rate of 6.6% in the forecast period of 2024-2032. With this growth rate, the number of cases is likely to reach nearly 41.40 million by 2032.

Introduction

Exosomes are small membrane vesicles of endocytic origin that are released from various cells in culture and are formed by plasma membrane fusion with the intermediate intracellular compartment and multivesicular body (MVB) fusion.

Exosomes are nano-sized vesicles capable of carrying DNA, small RNA, non-coding RNA, and lipids, with or without direct cell-to-cell communication, representing a new method of cell-to-cell communication.

Exosomes play a vital role in immune responses , viral pathogenicity, pregnancy, cardiovascular disease, central nervous system disease, and cancer progression. Biomolecules, including proteins, metabolites, and nucleic acids, are delivered to target cells by exosomes to adjust biological responses.

Exosomes  are designed to deliver variety of therapeutic payloads, including short-interference ribonucleic acids (RNAs), antiallergic oligonucleotides, chemotherapeutic agents, and immunomodulatory agents, and direct their delivery to the desired targets. Liquid biopsy, based on exosome vesicle, can be used to diagnose and determine prognosis in patients with cancer and other diseases. Therefore, the increase in cancer cases in hospitals directly increases the demand for the drugs.

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According to the global exosomes drug market research report, the market can be categorised into the following segments:

Market Breakup by Biomolecule Type

• Non-Coding RNAs

• mRNA (exoRNA)

• Proteins/ Peptides

• DNA Fragments 

• Lipids

Market Breakup by Product Type

• Kits

• Reagents

• Instruments

Market Breakup by Application

• Biomarkers

• Drug Delivery System

• Vaccine Development

• Therapeutic Agents

• Others

Market Breakup by Disease Type

• Cancer Disease

• Cardiovascular Disease 

• Neurodegenerative Disease 

• Tissue Regeneration 

• Infectious Disease 

• Others

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Market Breakup by Region

• North America

United States of America

Canada

• Europe

United Kingdom

Germany

France

Italy

Others

• Asia Pacific

China

Japan

India

ASEAN

Australia

Others

• Latin America

Brazil

Argentina

Mexico

Others

• Middle East and Africa

Saudi Arabia

United Arab Emirates

Nigeria

South Africa

Others

Market Scenario

The rapid growth of cancer disease drives the growth of the exosomes drug market. The rising demand for advanced drug therapies and potential applications of exosomes in diagnostics are expected to drive the market growth further in the coming years.

The market is primarily driven by the rising cases of cancer, followed by other infectious disease. Advanced exosomes technology in drug development and discovery provides valuable insights into heterogeneity and biological function, enabling us to exploit the therapeutic and diagnostic potential in cancer and infectious diseases. Therefore, the development of medical technology is driving the growth of global exosomes drug market.

The increasing demand for drug therapy in the pharmaceutical and biopharmaceutical fields can be attributed to the potential of exosomes technology as a diagnostic and therapeutic tool used in the treatment of various diseases, such as neurodegeneration, cardiovascular dysfunction, and cancer.

The potential applications of exosomes in cancer diagnostics and the development of precision medicine will increase the use of exosomes in the diagnostic and therapeutic industries, driving the growth of the market.

The rising application of these drugs due to its multifunctional properties has propelled its application in the treatment of various diseases like Alzheimer's disease, chronic heart failure, Parkinson's disease, liver cancer, breast cancer, lung cancer, and prostate cancer.

Regional Outlook for Global Exosomes Drug Market 

North America accounted for a significant share of the global market and is expected to grow rapidly during the forecast period. The leading position of the region can be attributed to factors like excellent healthcare infrastructure, effective government policies, large base of multinational corporations, and high public awareness about diagnosis and medical assistance.

On the other hand, the Asia Pacific region is also expected to witness significant growth in the coming years due to the higher presence of the emerging regions and their potential of growth. The regional market is likely to witness further growth due to the competitive strategies that are adopted by players to conduct research and development activities in this sector. Also, the growth of various pharmaceutical companies in this region is another factor that is fuelling the growth of exosomes drug market.

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Therapeutic Landscape

The exosomes drug market has been growing at a rapid rate owing to its multipurpose uses. Exosomes have been a preferred approach for treatment for various disease, including Alzheimer’s disease and COVID-19, among others. Exosomes find extensive clinical applications in the treatment of various diseases as a cell-free alternative for tissue regeneration using therapeutic cargo components, bypassing immune rejection and cytotoxicity.

Stem cell-derived exosomes help harness the anti-inflammatory and regenerative properties of parent cells. Thus, it is possible to design outpatient treatment of respiratory viral diseases, including SARS-CoV-2.

According to a few research studies, exosomes have generated positive results as mediators of intercellular communication, potentially delivering the functional proteins, mRNA transcripts, and miRNAs to cells throughout the body.

Research on exosomes applications is advancing rapidly, but the development of exosome-based therapy, especially the production of exosome formulations, has many difficulties due to low productivity and heterogeneity. Moreover, there are several barriers to the methods of storage, optimisation, and isolation of exosome formulations.

Clinical Landscape

Exosomes are associated with immune responses, viral pathogenesis, pregnancy, cardiovascular disease, diseases related to the central nervous system and the development of cancer. Exosomes do not only aid the diagnosis of diseases but also have therapeutic potential for controlling many diseases.

ExoFlo is a new clinical drug that has not been approved by the Food and Drug Administration. It is a product of extracellular vesicles isolated from human bone marrow stem cells or stromal cells (MSCs). The drug is in phase 2 of clinical development for the treatment of COVID-19, ARDS, and viral pneumonia.

Progenza is developed by Regeneus and is currently in development stage II for osteoarthritis and preclinical stages for neuropathic pain. Progenza is a cellular therapy that targets pain and inflammation, used to improve the tissues where the Secretome is present, and the Mesenchymal Signaling Cells (MSCs) themselves.

Competitive Landscape

The report gives an in-depth analysis of the key players involved in the global exosomes drug market, sponsors manufacturing the drugs, and putting them through trials to get FDA approvals. The companies included in the market are as follows:

• Danaher Corporation (Beckman Coulter Inc.)

• Hologic Inc.

• Lonza Group AG

• Fujifilm Holdings Corporation

• Miltenyi Biotec GmbH

• Qiagen N.V.

• Thermo Fisher Scientific Inc.

• JSR Corporation (MBL International)

• Illumina, Inc.

• Takara Bio Inc.

• Malvern Instruments Ltd. (Spectris Plc Company)

• Abcam Plc.

• Ampersand Capital Partner (New England Peptide, Inc.)

• Evox Therapeutics Ltd.

Key Highlights of the Report

Exosomes Drug Market Report Snapshots

Exosomes Drug Market Size

Exosomes Drug Market Regional Analysis

Exosomes Drug Companies