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The chronic inflammatory demyelinating polyneuropathy therapeutics market is expected to grow at a CAGR of 6.60% during the forecast period of 2024-2032, driven by the rising introduction of new therapeutic options and increased R&D activities focused on managing the disorder across the 8 major markets.
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Chronic inflammatory demyelinating polyneuropathy (CIDP) is defined as an auto-immune disorder in which the immune system attacks the myelin, which protects the body’s nerves. The common treatments for this neurological disorder include corticosteroids, plasma exchange, intravenous immunoglobulins, and chronic immunosuppressive agents. These therapeutics are either taken alone or in combination with two or more drugs.
The increase in healthcare spending by the government of emerging economies to improve neurological care is likely to augment the demand for chronic inflammatory demyelinating polyneuropathy therapeutics market. Moreover, the market is anticipated to be aided by the growing FDA approvals of immunoglobulin CDIP therapeutics which is propelling the production of CDIP drugs. Strategic collaborations between pharmaceutical laboratories aimed towards providing high-quality CDIP therapeutics are projected to provide impetus to the growth of the market in the coming years.
Increasing Prevalence of Rising Chronic Inflammatory Demyelinating Polyneuropathy to Affect the Market Landscape Significantly
Recent data suggests that the prevalence of chronic inflammatory demyelinating polyneuropathy ranges from 0.7 to 10.3 cases per 100,000 individuals. In the United States, it is estimated that 5 to 7 people per 100,000 are suffering from this rare neuromuscular disorder. The acquired autoimmune disease tends to predominate in males, with a sex rate ratio reported to range from 1.5 to 4. The increasing prevalence of this neurological disorder is driving the demand for CIDP therapeutics. In addition, the incidence is known to increase with advancing age. Thus, the market is being positively navigated by the rise in the geriatric population and sedentary lifestyles led by working-class adults.
Growth in Approval of Novel Therapeutics to Meet Rising Chronic Inflammatory Demyelinating Polyneuropathy Therapeutics Market Demand
In January 2024, the US Food and Drug Administration (FDA) approved Takeda Pharmaceuticals’s HyQvia for the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP). Indicated as a maintenance therapy for adults with CIDP, HyQvia is the only FDA-cleared combination of immunoglobulin (IG) and hyaluronidase. The approval was based on the positive results demonstrated in the late-stage ADVANCE-CIDP 1 study. This IG therapy is administered as a subcutaneous infusion and can also be self-administered after appropriate training. The surge in approval of such personalized maintenance treatment alternatives for CIDP is likely to drive the market growth in the forecast period.
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The market is witnessing several trends and developments to improve the current global scenario. Some of the notable trends are as follows:
Key Trends | Impact |
Increased Utilization of Immunoglobulin Therapies | One of the major market trends is the increased utilization of intravenous immunoglobulin (IVIG) and subcutaneous immunoglobulin (SCIG) therapies to manage CIDP, which is expected to augment the market demand. These treatments are known for their efficacy in reducing symptoms and improving the patient’s quality of life. |
Advancements in Diagnostic Technologies | The rising advancements in diagnostic techniques, such as the availability of innovative electromyography (EMG) equipment, high-resolution MRI, and nerve conduction studies, are resulting in early and more accurate diagnosis of CIDP. Early diagnosis leads to timely intervention and improves patient outcomes, thereby impacting the chronic inflammatory demyelinating polyneuropathy therapeutics market share. |
Rising Healthcare Expenditure | The rising healthcare spending allows for greater access to advanced treatments for CIDP and also supports the development of novel therapeutics. Increased government initiatives and healthcare reforms along with this trend are ensuring easier access to these medications and are projected to shape the market dynamics. |
Growing Preference for Subcutaneous Therapies | The market is witnessing a rising preference for subcutaneous administration of immunoglobulin due to its associated convenience and ability for home administration. Consequently, subcutaneous immunoglobulin (SCIg) is anticipated to witness increased demand as a maintenance treatment for adult patients with CIDP. |
Market Breakup by Drug Type
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Market Breakup by Gender
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Market Breakup by Distribution Channel
Market Breakup by Region
Market Segmentation Based on Drug Type is Anticipated to Witness Substantial Growth
The market segmentation by drug type includes corticosteroids, intravenous immunoglobulin therapy (IVIG), plasmapheresis (plasma exchange), immunotherapy, and stem cell transplant, among others. Corticosteroids reduce inflammation and hamper the efficiency of the immune system and are known to improve the health of around 60% of patients. Hence, this drug type is witnessing a significant demand in the healthcare industry. In addition to this, these drugs are easy to administer, relatively cheap as compared to their counterparts, and offer long-term remission in chronic inflammatory demyelinating polyneuropathy. Consequently, this drug type is poised to augment the chronic inflammatory demyelinating polyneuropathy therapeutics market demand.
In addition, the response rate of corticosteroids is high, which is anticipated to be a major driving factor of the segment in the forecast period. In the coming years, the anticipated increase in demand for corticosteroids such as prednisone and prednisolone, as orally taken tablets, is likely to provide impetus to the segment.
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The segmentation based on the region includes the United States, EU-4 (Germany, France, Italy, Spain), and the United Kingdom, Japan, and India. The United States holds a substantial market value driven by the presence of technologically advanced healthcare infrastructure and a favourable regulatory environment. A significant portion of the population in the regional market gets affected by chronic inflammatory demyelinating polyneuropathy (CIDP) every year, which directly impacts the market demand. Increased initiatives by the government along with social media campaigns spreading awareness about CIDP are likely to stimulate the market growth in the coming years. Along with United States, EU-4 and the United Kingdom is also expected a notable market share in the forecast period.
The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:
CSL Behring
Global biotechnology company CSL Behring is a leading manufacturer of plasma-derived and recombination therapeutics. The company's Hizentra®, a 20% liquid IgG product for subcutaneous administration, is indicated as a maintenance therapy for adult patients with chronic inflammatory demyelinating polyneuropathy (CIDP).
ADMA Biologics, Inc.
This biopharmaceutical company specializes in the development of specialty plasma-derived biologics that can help treat immune deficiencies and infectious diseases. The company intends to improve the efficacy and safety of its existing therapies through rigorous research activities and clinical trials.
Pfizer Inc.
Pfizer Inc. invests heavily in the clinical development of various drugs aimed to treat neurological and autoimmune conditions and thus significantly contributes to the chronic inflammatory demyelinating polyneuropathy therapeutics market growth. In February 2021 , the United States Food and Drug Administration (FDA) approved Pfizer's Panzyga® (Immune Globulin Intravenous [Human] – ifas 10 percent Liquid Preparation) indicated to treat chronic inflammatory demyelinating polyneuropathy.
UCB S.A.
Headquartered in Belgium, this multinational biopharmaceutical company has a robust presence in the market. It is involved in the clinical development of CIDP therapeutics.
Other key players in the market include Bio Products Laboratory Ltd., Grifols, Teva Pharmaceutical Industries Ltd., and Sun Pharmaceutical Industries Ltd.
REPORT FEATURES | DETAILS |
Base Year | 2023 |
Historical Period | 2017-2023 |
Forecast Period | 2024-2032 |
Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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