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The chronic fatigue syndrome treatment market was valued at USD 49.18 million in 2023, driven by increased clinical research to find effective treatments across the 8 major markets. The market is expected to grow at a CAGR of 4.2% during the forecast period of 2024-2032, with the values likely to reach USD 71.22 million by 2032.
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Chronic fatigue syndrome (CFS) is a medical condition that causes extreme fatigue or tiredness that does not go away with rest and cannot be explained by an underlying medical condition. Chronic fatigue syndrome is also known as myalgic encephalomyelitis (ME) or systemic exertion intolerance disease (SEID). Because there is no specific test for chronic fatigue syndrome, it is diagnosed based on the symptoms and the exclusion of other conditions that could be causing the symptoms. While there is currently no cure for chronic fatigue syndrome, there are treatments that may help manage the condition.
Recent data reveals that 1% of the adult population in the United States is affected by chronic fatigue syndrome. Women are 2-4 times more likely than men to be diagnosed with the condition. Chronic fatigue syndrome is most common in people in their 40s and 50s. Blacks and Latins are reported to be affected more frequently and severely than other groups.
The chronic fatigue syndrome treatment market is driven by the growing awareness and understanding of the syndrome, which is leading to a higher diagnosis rate and a substantial demand for effective treatment options. This rising demand also fuels the research and development in the market along with attracting pharmaceutical companies to invest in new treatments. The increase in the number of clinical trials and research collaborations aimed at finding evidence-based treatments is anticipated to support the market growth in the forecast period.
Increased Clinical Research to Drive Market Growth
In July 2024, a six-year follow-up data that analyzed two clinical trials evaluating treatments for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), the RituxME trial and the CycloME trial, revealed that cyclophosphamide is linked with greater and more lasting improvements compared to rituximab or placebo. The study results also indicate that an autoimmune pathomechanism might be associated with chronic fatigue syndrome, which makes immunomodulatory drugs a potential treatment option. The rise in such research studies directed at finding evidence-based treatments are projected to fuel market growth.
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The market is witnessing several trends and developments to improve the current global scenario. Some of the notable trends are as follows:
Focus on Immunomodulatory Treatments to Affect the Market Landscape Significantly
One of the major market trends is the increasing focus on immunomodulatory therapies driven by the growing evidence that chronic fatigue syndrome may involve an immune system dysfunction. For instance, Rintatolimod, an immunomodulator and antiviral drug was recently approved for the treatment of chronic fatigue syndrome in Canada and Europe. However, this immunomodulator drug is yet to be approved by the United States FDA.
Increased Emphasis on Biomarker Discovery to Elevate the Chronic Fatigue Syndrome Treatment Market Value
The market is experiencing a growing emphasis on the discovery and validation of biomarkers, which are essential for improving the diagnosis and treatment of chronic fatigue syndrome. For example, in January 2024, a study published in the Journal of Clinical Medicine revealed that MedUni Vienna researchers identified potential biomarkers based on the immunological stratification in chronic fatigue syndrome patients that show promise in improving long-lasting fatigue. The discovery of such biomarkers that could help in developing diagnostic tools and personalized treatment plans are set to elevate the market value in the forecast period.
Rising Adoption of Cognitive Behavioral Therapy (CBT) Likely to Influence Chronic Fatigue Syndrome Treatment Market Dynamics
The market is witnessing a rising trend toward integrating cognitive behavioral therapy (CBT) into overall treatment plans for managing chronic fatigue syndrome. CBT has shown effectiveness in helping patients manage symptoms like fatigue, depression, and anxiety. The increased emphasis on providing patients with strategies to deal with the psychological impacts of chronic fatigue syndrome is likely to shape the market dynamics.
Growing Interest in Alternative and Complementary Therapies to Augment Chronic Fatigue Syndrome Treatment Market Demand
The rising interest in alternative and complementary therapies for managing symptoms of chronic fatigue syndrome is a significant market trend. Among patients seeking non-pharmacological treatment options, the preference towards meditation, yoga, acupuncture, and nutritional therapy is increasing. This trend is particularly growing in patients who are experiencing side effects from conventional medications and is anticipated to impact market demand in the coming years.
Market Breakup by Treatment
Market Breakup by Route of Administration
Market Breakup by End User
Market Breakup by Region
Based on the treatment, the market share is segmented into antidepressants, pain relievers, sleep aids, and immunomodulators, among others. The condition cannot be managed with just one treatment since the symptoms are dynamic. Chronic fatigue syndrome causes a symptom of depression in many cases. Low-dose antidepressant therapy or a referral to a mental health provider may be required. If lifestyle changes do not result in a restful night's sleep, sleep aids are often recommended. Pain relievers are also commonly used to manage aches and joint pain caused by chronic fatigue syndrome.
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Based on the region, the market includes the United States, EU-4 (Germany, France, Italy, Spain), and the United Kingdom, Japan, and India. The United States dominates the market due to rising healthcare expenditures, a well-developed healthcare sector, a large patient pool, and government support for research and development. The region is likely to witness market growth in the forecast period as well due to the rising prevalence of the condition and the increasing patient awareness. Further, the growth of patient advocacy groups and support networks working towards advancing care for chronic fatigue syndrome patients is poised to aid market expansion in the region.
The key features of the market report comprise patent analysis, clinical trial analysis, grant analysis, funding and investment analysis, and strategic initiatives by the leading key players. The major companies in the market are as follows:
Pfizer Inc.
Pfizer is a dominant player in the market known for investing heavily in the areas of neuroscience and immunology. The company is actively exploring novel drug candidates for chronic neurological conditions, including chronic fatigue syndrome.
Torrent Pharmaceuticals Ltd.
Indian multinational pharmaceutical company Torrent Pharmaceuticals Ltd. boasts a robust pipeline of products aimed at treating neurological and psychiatric disorders. The company leverages strategic acquisitions to expand its market presence.
Cadila Pharmaceuticals Ltd.
Cadila Pharmaceuticals Ltd., a leading pharmaceutical company based in India, is engaged in the development of treatments for a range of chronic conditions including therapeutic solutions that could benefit patients with chronic fatigue syndrome.
Mylan Pharmaceuticals Inc.
Mylan Pharmaceuticals Inc., headquartered in West Virginia, United States, is a generic and specialty pharmaceutical company. Its antidepressant drugs are often used to manage depressive symptoms in chronic fatigue syndrome patients.
Other key players in the market include Mallinckrodt Pharmaceuticals, Eli Lilly and Company, Novartis AG, Sun Pharmaceutical Industries Ltd., AIM ImmunoTech Inc., and H Lundbeck A/S.
REPORT FEATURES | DETAILS |
Base Year | 2023 |
Historical Period | 2017-2023 |
Forecast Period | 2024-2032 |
Scope of the Report |
Historical and Forecast Trends, Industry Drivers and Constraints, Historical and Forecast Market Analysis by Segment:
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Breakup by Treatment |
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Breakup by Route of Administration |
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Breakup by End User |
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Breakup by Region |
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Market Dynamics |
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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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