Global Ankylosing Spondylitis Treatment Market Report and Forecast 2024-2032

Global Ankylosing Spondylitis Treatment Market Outlook

The global ankylosing spondylitis treatment market size attained a value of USD 5.02 billion in 2023. The market is expected to grow further at a CAGR of 8.1% during the forecast period of 2024-2032 to attain a value of USD 10.11 billion by 2032, driven by the rising prevalence of the condition due to inactive lifestyle of people.

Ankylosing Spondylitis Treatment Market: Introduction

Ankylosing spondylitis or axial spondylarthritis is a type of chronic arthritis that severely affects the spine, lower back, and the hips and leads to inflammation in these parts. Ankylosing spondylitis causes severe inflammation in the sacroiliac joints, which are located amidst the spinal and pelvis base. It is a disease which can trigger the bones in the vertebrae to fuse, over a period of time. The condition often starts after the age of 20 due to factors like inactive lifestyle, bad posture, as well as genetic factors. People suffering from diseases like Crohn’s disease, Psoriasis, or Ulcerative colitis are also at a high risk of getting ankylosing spondylitis.

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Inflammation or sacroiliitis is among the primary symptoms of this condition, and it often spreads further to other parts of the body like the spinal cord, which is made up of vertebrae and other bones, and even eyes. This inflammation can even result in the formation of additional calcium around the bone, which can eventually form up as a new bone and further complicate the problem.

The symptoms of the condition can vary from person to person. While some may experience sharp pain, some might not have any symptoms at all. The most common symptoms of the condition include severe pain (continuous or in intervals) in different parts like the joint between the spinal base and the pelvis, vertebrae, lower back, places where tendons and ligaments attach to bones, and it can even go down to the back of the heel. Other parts that are often affected due to the condition include the cartilage, hip and shoulder joints, among others.

Ankylosing spondylitis can be of two types-

• Ankylosing Spondylitis/ Axial Spondylarthritis- When the condition can be detected through X-ray.

• Nonradiographic Axial Spondyloarthritis- When the condition needs more tests like imaging tests and blood tests.

Ankylosing spondylitis does not have any cure as such but the progression of the condition can be restricted to a significant extent with regular treatment and changes in lifestyles and posture. While the condition does not pose any direct threat to life, it might lead to certain complications if not treated timely. These potential complications include stiffness or inflexibility of the spine, inflammation in the eyes, compression fractures, and even heart problems.

Ankylosing Spondylitis Treatment Market Segmentations

The market can be categorised into drug type, indication type, treatment methods, treatment channel, and major regions.

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Market Breakup by Drug Type

• Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

• TNF Inhibitors

• Others

Market Breakup by Indication Type

• Reactive Arthritis

• Psoriatic Arthritis

• IBD Associated Arthritis

• Juvenile Spondyloarthropathy

• Undifferentiated Spondyloarthropathy

• Others

Market Breakup by Treatment Method

• Physiotherapy and Exercise

• Painkillers

• Biological Treatments

• Corticosteroids

• Disease Modifying Anti Rheumatic Drugs (DMARDs)

• Surgery

• Others

Market by Treatment Channel

• Public

• Private

Market Breakup by Region

• North America
  • United States of America
  • Canada
• Europe
  • United Kingdom
  • Germany
  • France
  • Italy
  • Others
• Asia Pacific
  • China
  • Japan
  • India
  • ASEAN
  • Australia
  • Others
• Latin America
  • Brazil
  • Argentina
  • Mexico
  • Others
• Middle East and Africa
  • Saudi Arabia
  • United Arab Emirates
  • Nigeria
  • South Africa
  • Others

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Ankylosing Spondylitis Treatment Market- Epidemiology

The condition can start affecting people right from the age of 20 and continue troubling them thereafter if not treated timely. Based on gender, men are more likely to be in this condition than women and the symptoms also differ between men and women. Based on race, the condition is more likely to affect Americans than Africans.  

Ankylosing Spondylitis Treatment Market- Therapeutic Landscape

Ankylosing spondylitis is a lifelong condition and does not have any permanent cure. While there are no cures available for the condition, there are various treatment options available in the market. Along with these treatments, the patient can also practise exercises to limit further progression of the condition. Some of these treatments are:

• Exercise: Exercise is the first and the foremost advice given by the doctors. These exercises would help the patient reduce the pain as well as improve the posture or at least restrict any further damage to the spine. The condition is caused by inactivity and adopting an active lifestyle can prove to be beneficial.

• NSAIDs or Nonsteroidal Anti-Inflammatory Drugs: Some of the most common NSAIDs include drugs like ibuprofen (Advil®) and naproxen (Aleve®), among others. These drugs can provide immediate but term relief from pain and inflammation.

• DMARDs or Disease Modifying Anti-Rheumatic Drugs: Sulfasalazine is the most common DMARDs in the market. It can help reduce the inflammation, swelling, and pain in the joints. The new DMARDs called biologics, like TNF or tumour necrosis factor and IL-17 or interleukin inhibitors, can alter the immune system to manage inflammation.

• Corticosteroids: These are available in the form of injections and can release the pain and inflammation.

• Surgery: It is mostly the last resort for the patients when nothing else helps. With this surgery, an artificial joint is implanted to correct the curved spine.

• Physiotherapy: A physiotherapist can significantly help the patient manage the inflammation and swelling and can also recommend a set of customised exercises. They can also recommend and help with aquatic or hydrotherapy which can help ease the spinal cord.

Key Players in the Global Ankylosing Spondylitis Treatment Market

The major companies working on the drugs and treatment of the condition and investing in the clinical trials include the following:

• Abvie, Inc.

• Amgen Inc.

• Eli Lilly & Company

• Gilead Sciences

• Johnson & Johnson (Janssen)

• Pfizer Inc.

• Novartis AG

Key Highlights of the Report