Polycystic Kidney Disease Drugs Market Overview
Polycystic kidney disease (PKD) refers to a genetic disorder that is characterized by the formation of fluid-filled sacs (cysts) in the kidneys. The disease can result in serious complications, including high blood pressure and kidney failure. The increasing prevalence of polycystic kidney disease, especially the autosomal dominant form, is expected to fuel the market growth. The rising advancements in drug development and the growth in new drug approvals are poised to augment the market demand. Additionally, the growing focus on symptom management and the rise in clinical trials are likely to influence the polycystic kidney disease drugs market landscape.
Key Findings
- Recent data indicates that there are 500,000 people living with autosomal dominant polycystic kidney disease in the United States. The increasing prevalence of this polycystic kidney disease is one of the primary drivers of the market.
- The surge in the number of clinical trials aimed at the development of new therapies and the rising demand for medications that can manage the symptoms of the disease are projected to elevate the market value.
- In May 2022, the PKD Charity and Kidney Research UK, in a collaborative initiative, announced a grant of EUR 537,000 to support three research projects that aim to improve the lives of polycystic kidney disease patients. Such substantial research investments are likely to bolster market growth in the forecast period.
Polycystic Kidney Disease Drugs Market Demand Drivers
Autosomal dominant polycystic kidney disease constitutes the more prevalent form of polycystic kidney disease, affecting 1 in 400 to 1000 individuals. On the other hand, autosomal recessive polycystic kidney is reported to have an estimated prevalence of 1 in 20,000 to 40,000 people. The increasing prevalence of polycystic kidney disease is one of the key factors propelling the demand for effective medications that can slow disease progression and manage symptoms.
Polycystic Kidney Disease Drugs Market Segmentation Analysis
The Disease Type Segment is Anticipated to Witness Significant Growth in the Forecast Period
Based on the disease type, the market segmentation includes autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD), among other rare forms. Autosomal dominant polycystic kidney disease is an inherited genetic disorder that causes the development of numerous cysts in the kidneys and results in progressive kidney damage over time. The drug tolvaptan shows high efficacy in slowing the progression of kidney function decline in autosomal dominant polycystic kidney disease and thus is commonly used for the treatment of the condition. The market is witnessing a growing demand for medications that help in symptom management of ADPKD such as hypertension, pain, and kidney infections, which is likely to contribute to the market expansion in the coming years.
The market report also offers insights based on the mechanism of action, route of administration, end-user, and region.
Polycystic Kidney Disease Drugs Market: Competitive Landscape
- In June 2024, clinical-stage biopharmaceutical company Regulus Therapeutics Inc. reported positive topline findings from the third cohort of patients in its double-blind, placebo-controlled Phase 1b MAD clinical trial of a novel, next-generation oligonucleotide, RGLS8429, for the treatment of autosomal dominant polycystic kidney disease.
- In April 2024, Alebund, a clinical-stage biopharma focused on developing novel treatments for kidney diseases and associated complications, revealed that its internally developed investigational drug AP303 received orphan drug designation (ODD) from the US Food and Drug Administration for the treatment of autosomal dominant polycystic kidney disease.
- Other players involved in the market include Otsuka Pharmaceutical Co., Ltd., Cadwell Industries, Inc., Nihon Kohden Corporation, Esumedics GmbH, Neurosoft, Mitsar, Allengers Medical Systems Limited, and Lifelines Neuro.
Polycystic Kidney Disease Drugs Market Analysis by Region
The United States is Projected to Lead the Market Share
The market segmentation by region includes the United States, EU-4 (Germany, France, Italy, Spain), and the United Kingdom, Japan, and India. The United States is projected to dominate the market for polycystic kidney disease drugs due to the high prevalence of autosomal dominant polycystic kidney disease and the presence of a well-established healthcare system. The robust regulatory framework and the growing demand for innovative therapies also support the market growth. Moreover, the rising R&D investment in rare and genetic diseases and increasing healthcare spending are anticipated to boost the market expansion in the country.
Key Offerings of the Report
- The EMR report gives an overview of the market for polycystic kidney disease drugs for the time span of (2017-2023) and (2024-2032).
- The report also offers historical (2017-2023) and forecast (2024-2032) market information for the disease type, mechanism of action, route of administration, end user, and region of the market.
- The report analyses the market dynamics, covering the key demand and price indicators in the market, along with providing an assessment of the SWOT and Porter’s Five Forces models.
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