Global Bone Morphogenetic Proteins Market to Grow at a CAGR of 2.3% During the Period 2024-2032, Driven by Applications in Domains Including Dentistry, Orthopaedics, Sport and Rehabilitation

The global bone morphogenetic proteins market is expected to be driven by uses in processes during the formation and maintenance of organs such as bone, cartilage, muscle, kidney and blood vessels.

Bone morphogenetic proteins are naturally occurring molecules first recognized by Urist in 1965 as proteins existing in demineralized bone matrix and capable of osteoinduction in ectopic sites in rats. Apart from BMP-1 (a metalloprotease), Bone morphogenetic proteins form a sub-class of the transforming growth factor β (TGF-β) superfamily. Hitherto, nearly twenty bone morphogenetic proteins have been discovered, but not all are indeed osteogenic molecules. BMP-2 and BMP-7 are considered stronger inducers of bone and cartilage formation. While BMP-4, BMP-5, BMP-6, BMP-8, BMP-9, and BMP-10 also assist bone formation, BMP-3 and BMP-13 act as BMP inhibitors.

Due to their osteogenic effect, bone morphogenetic proteins are employed in several areas of medicine, including dentistry, orthopaedics, sport and rehabilitation. Such applications are expected to drive the global bone morphogenetic proteins market. Recombinant human bone morphogenetic proteins (rhBMPs) are administered to the bone grafting site through surgery. Bone morphogenetic protein 2 (BMP-2) plays an important role in embryonic dorsalventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. Bone morphogenetic protein 2 is an effective osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. Bone morphogenetic protein 2 also plays a key role in cardiac morphogenesis and is expressed in multiple tissues including lung, spleen, brain, liver, prostate ovary and small intestine.

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It is suggested that some bone morphogenetic proteins and some associated factors could be involved in embryonic development. Osteogenin and related bone morphogenetic proteins are reported to promote additional successive steps in the endochondral bone formation cascade by functioning as potent chemoattractants for circulating monocytes and by encouraging, among other things, the synthesis and secretion of TGF-beta-1 by monocytes.

Key Findings of the Report:

• The global bone morphogenetic proteins market is expected to be driven by applications in processes during the formation and maintenance of organs such as bone, cartilage, muscle, kidney and blood vessels. 

• Advanced solutions are likely to boost market growth.

• North America, Europe and Asia are likely to be key markets.

Market Analysis by Type, Application and Region:

• By type, the market is segmented into Recombinant Human Bone Morphogenetic Protein (rhBMP) – 2 and Recombinant Human Bone Morphogenetic Protein (rhBMP) -7.

• By application, the market is divided into Spinal Fusion, Trauma, Reconstructive Surgery, and Oral-maxillofacial.

• By region, the market is classified into North America, Europe, Asia Pacific, Latin America, and Middle East and Africa.

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