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According to the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA), treatment-resistant depression is defined as an inadequate response to at least two antidepressants despite adherence to the treatment and adequacy of the treatment trial. Current estimates suggest that about 30% of individuals with depression experience treatment-resistant depression.
Base Year
Historical Year
Forecast Year
Expert Market Research's “Treatment Resistant Depression Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of treatment resistant depression. It projects the future incidence and prevalence rates of treatment resistant depression across various populations. The study covers age and type as major determinants of the treatment resistant depression-affected population. The report highlights patterns in the prevalence of treatment resistant depression over time and projects future trends based on multiple variables.
The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of treatment resistant depression in the 8 major markets.
Regions Covered
Treatment resistance depression (TRD) is a challenging and complex type of depression, where people with major depressive disorder fail to respond adequately to at least two different antidepressant treatments of appropriate dosage and duration. The exact cause of treatment resistance depression is not known but may involve a combination of genetic, environmental, and biological factors. This condition is linked with functional impairment and a higher likelihood of suicidal ideation. Treatment resistance depression is more prevalent in females and older adults and imposes a substantial healthcare burden.
Management of treatment-resistant depression typically includes trying different approaches when standard treatments don’t work, with the focus on finding the right combination of therapies. The affected patients are often switched to a different type of antidepressant, like tricyclic antidepressants (TCAs) or monoamine oxidase inhibitors (MAOIs), or prescribed additional medications, such as antipsychotics, lithium, or thyroid hormones, to boost the effects of antidepressants. Some healthcare providers also recommend a combination of antidepressants for better results.
The treatment resistant depression epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for treatment resistant depression by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for treatment resistant depression and their trends. The data is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.
The treatment resistant depression epidemiology data and findings for the United States, EU-4 (Germany, Spain, Italy, France), the United Kingdom, Japan, and India are also provided in the epidemiology section.
The epidemiology of treatment resistant depression varies significantly between countries due to differences in the treatment availability and accessibility, cultural attitudes toward mental health, diagnostic criteria, and socioeconomic factors. Genetic predispositions and lifestyle factors, such as diet, physical activity, and substance use, also influence the prevalence across populations. In India, the prevalence of depressive disorders is reported to be 2.7% by the National Mental Health Survey.
Country Specific Stats:
Country |
Prevalence (Unit) |
United States |
XX |
United Kingdom |
XX |
Germany |
XX |
Italy |
XX |
France |
XX |
Spain |
XX |
Japan |
XX |
India |
XX |
Treatment Resistant Depression Market
Treatment Resistant Depression Drug Pipeline Analysis
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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Report Features |
Details |
Base Year |
2024 |
Historical Period |
2018-2024 |
Forecast Period |
2025-2034 |
Geographies Covered |
|
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Australia
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India
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Philippines
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+63-287-899-028, +63-967-048-3306
United Kingdom
6 Gardner Place, Becketts Close, Feltham TW14 0BX, Greater London
+44-753-713-2163
United States
30 North Gould Street, Sheridan, WY 82801
+1-415-325-5166
Vietnam
193/26/4 St.no.6, Ward Binh Hung Hoa, Binh Tan District, Ho Chi Minh City
+84-865-399-124
United States (Head Office)
30 North Gould Street, Sheridan, WY 82801
+1-415-325-5166
Australia
63 Fiona Drive, Tamworth, NSW
+61-448-061-727
India
C130 Sector 2 Noida, Uttar Pradesh 201301
+91-723-689-1189
Philippines
40th Floor, PBCom Tower, 6795 Ayala Avenue Cor V.A Rufino St. Makati City, 1226.
+63-287-899-028, +63-967-048-3306
United Kingdom
6 Gardner Place, Becketts Close, Feltham TW14 0BX, Greater London
+44-753-713-2163
Vietnam
193/26/4 St.no.6, Ward Binh Hung Hoa, Binh Tan District, Ho Chi Minh City
+84-865-399-124
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