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HER2 non-small cell lung cancer refers to a type of lung cancer where the tumor cells express high levels of the HER2 protein. Nearly 50% to 75% of females are more prone to HER2-mutated NSCLC, indicating a high occurrence of HER2 non-small cell lung cancer (NSCLC) in females rather than in males. The HER2 non-small cell lung cancer (NSCLC) epidemiology forecast suggests an increasing recognition of HER2 alterations in NSCLC, with variations across different populations.
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Expert Market Research's “HER2 Non-Small Cell Lung Cancer Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of HER2 non-small cell lung cancer. It projects the future incidence and prevalence rates of HER2 non-small cell lung cancer cases across various populations. The study covers age and type as major determinants of the HER2 non-small cell lung cancer population. The report highlights patterns in the prevalence of HER2 non-small cell lung cancer over time and projects future trends based on multiple variables.
The report provides a comprehensive overview of the disease, as well as historical and projected data on HER2 non-small cell lung cancer epidemiology in the 8 major markets.
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HER2 non-small cell lung cancer (NSCLC) is a rare type of lung cancer. It happens when there are changes in the HER2 gene. These changes can include mutations, amplifications, or too much HER2 protein. HER2 alterations are more common in people who have never smoked and in Asian populations.
Most HER2 non-small cell lung cancer cases are a type of NSCLC called adenocarcinoma. HER2 changes usually don’t occur with other common mutations like EGFR or ALK, which are also known to drive lung cancer. It is important for patients to have molecular testing to check for HER2 and other mutations before starting HER2 non-small cell lung cancer treatment.
The HER2 non-small cell lung cancer epidemiology division offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for the HER2 non-small cell lung cancer epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for HER2 Non-Small Cell Lung Cancer and their trends. The HER2 non-small cell lung cancer detailed epidemiology segmentation is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.

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The HER2 non-small cell lung cancer epidemiology data and findings for the United States, EU-4 (Germany, Spain, Italy, France), the United Kingdom, Japan, and India are also provided in the epidemiology section.
The epidemiology of HER2 non-small cell lung cancer varies significantly between countries due to differences in factors such as hygiene practices and genetic factors, among others. In the United States, 1–6 .7% of cases of non-small cell lung cancer (NSCLC) have HER2 alterations. HER2 mutation, amplification, and overexpression are among these changes.
Targeted therapies that specifically target HER2 alterations are part of the treatment for HER2 non-small cell lung cancer (NSCLC). In patients with HER2 mutations, the antibody-drug conjugate trastuzumab deruxtecan has shown notable effectiveness. Tyrosine kinase inhibitors (such as neratinib and poziotinib) and chemotherapy are additional HER2 non-small cell lung cancer therapeutics for more comprehensive disease control.
Although its effectiveness in HER2-positive cases is still being investigated, immunotherapy may also be taken into consideration. The type of HER2 alteration, the cancer's stage, and the patient's general health are some of the factors that go into choosing a HER2 non-small cell lung cancer treatment. Clinical trials are still a crucial tool for investigating new treatments. Patients with this aggressive cancer type now have more options than chemotherapy thanks to targeted therapies like HER2 inhibitors.
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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Base Year |
2025 |
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Historical Period |
2019-2025 |
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Forecast Period |
2026-2035 |
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