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Report Overview

Hemophilia A, which is characterized by low levels of factor VIII, is 3 to 4 times as common as hemophilia B. It is estimated that more than 400,000 males are affected by this X-linked hereditary disorder of hemostasis across the world, with many people remaining undiagnosed.

2024

Base Year

2018-2024

Historical Year

2025-2034

Forecast Year

Hemophilia A Epidemiology Forecast Report Coverage

Expert Market Research's “Hemophilia A Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of hemophilia A. It projects the future incidence and prevalence rates of Hemophilia A across various populations. The study covers age and type as major determinants of the hemophilia A-affected population. The report highlights patterns in the prevalence of Hemophilia A over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of hemophilia A in the 8 major markets.

Regions Covered

  • The United States
  • Germany
  • France
  • Italy
  • Spain
  • The United Kingdom
  • Japan
  • India

Hemophilia A: Disease Overview

Hemophilia A is a rare X-linked recessive condition caused by a deficiency or absence of clotting factor VIII (FVIII). It primarily affects males, while females are typically carriers. Common symptoms include prolonged or spontaneous bleeding, easy bruising, joint swelling, and internal bleeding. Based on the FVIII levels and severity of the bleeding episodes, the disease is classified as severe, moderate, and mild. Severe cases are reported to be characterized by frequent spontaneous bleeding into muscles and joints.

Hemophilia A: Treatment Overview

Treatment for hemophilia A is focused on managing bleeding episodes and preventing complications. Factor replacement therapy is the primary treatment approach that replaces the deficient clotting factor. To prevent spontaneous bleeding and joint damage, regular infusion of FVIII concentrates is also opted as a prophylactic treatment. Desmopressin (DDAVP) is used for mild hemophilia A, which works by stimulating the release of stored factor VIII from the blood vessels. Emerging treatments, such as gene therapy, are expected to provide a long-term or permanent solution.

Epidemiology

The hemophilia A epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for hemophilia A by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for hemophilia A and their trends. The data is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools.

  • Global estimates indicate that hemophilia A ranks as the most common X-linked hereditary disorder of hemostasis, with over 400,000 males affected by the condition.
  • According to the Centers for Disease Control and Prevention (CDC), hemophilia A occurs 3 to 4 times more commonly than hemophilia B.
  • Studies report that hemophilia A is attributed to 80% of all hemophilia cases and is estimated to occur in 1 out of 5,000 males.
  • As per Orphanet, the prevalence of hemophilia A is reported to be about 1 in 6,000 males, with the condition primarily affecting men. However, it is observed that women may also be symptomatic with a milder clinical presentation of the disease.

Country-wise Hemophilia A Epidemiology

The hemophilia A epidemiology data and findings for the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

The epidemiology of hemophilia A varies significantly between countries due to differences in genetic backgrounds, socioeconomic and cultural factors, healthcare access, and diagnostic practices. Variations in healthcare infrastructure and awareness also influence reported cases and disease outcomes. As per the Haemophilia and Health Collective of North (HHCN), India is considered to have the second-largest population of hemophilia patients worldwide, with nearly 136,000 cases of hemophilia A.

Country Specific Stats:

Country

Prevalence (Unit)

United States

XX

United Kingdom

XX

Germany

XX

Italy

XX

France

XX

Spain

XX

Japan

XX

India

XX

Scope of the Report

  • The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of hemophilia A based on several factors.
  • The Hemophilia A Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
  • The report helps to identify the patient population, and the unmet needs of hemophilia A are highlighted along with an assessment of the disease's risk and burden.

Key Questions Answered

  • What are the key findings of hemophilia A epidemiology in the 8 major markets?
  • What will be the total number of patients with hemophilia A across the 8 major markets during the forecast period?
  • What was the country-wise prevalence of hemophilia A in the 8 major markets in the historical period?
  • Which country will have the highest number of hemophilia A patients during the forecast period of 2025-2034?
  • Which key factors would influence the shift in the patient population of hemophilia A during the forecast period of 2025-2034?
  • What are the currently available treatments for hemophilia A?
  • What are the disease risks, signs, symptoms, and unmet needs of hemophilia A?

Related Reports

Global Haemophilia Treatment Market Report and Forecast

Hemophilia B Epidemiology Forecast

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Base Year

2024

Historical Period

2018-2024

Forecast Period

2025-2034

Geographies Covered

  • United States
  • Germany
  • Italy
  • France
  • Spain
  • United Kingdom
  • Japan
  • India

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