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Coagulation factor deficiencies, such as hemophilia, are hereditary disorders that cause abnormal bleeding. Hemophilia A affects 1 in 5000 males, with over 400,000 males affected globally. In the United States, 33,000 males live with hemophilia. Treatment involves clotting factor replacement and other supportive therapies to manage bleeding episodes.
Base Year
Historical Year
Forecast Year
Expert Market Research's “Coagulation Factor Deficiency Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of coagulation factor deficiency. It projects the future incidence and prevalence rates of coagulation factor deficiency across various populations.  The study covers age and type as major determinants of the coagulation factor deficiency-affected population. The report highlights patterns in the prevalence of coagulation factor deficiency over time and projects future trends based on multiple variables.
The report provides a comprehensive overview of the disease, as well as historical and projected data on the epidemiology of coagulation factor deficiency in the 8 major markets.
Regions Covered
Coagulation factor deficiencies, including hemophilia, are conditions where the blood’s ability to clot is impaired due to a lack or deficiency of specific clotting factors. Hemophilia, the most common of these disorders, is X-linked and primarily affects males. Hemophilia A is caused by a deficiency in factor VIII, while Hemophilia B results from a lack of factor IX. Symptoms include prolonged bleeding, easy bruising, and spontaneous internal bleeding. Diagnosis is based on clotting tests, and treatment often involves replacement therapies with clotting factors. Prevention of bleeding episodes and managing complications are key to improving quality of life.
Treatment for coagulation factor deficiencies, such as hemophilia, primarily involves replacing the missing clotting factors. Factor replacement therapy is the cornerstone, with recombinant clotting factors or plasma-derived concentrates administered intravenously. For mild cases, infusions may be given on-demand during bleeding episodes, while severe cases may require regular prophylactic treatments to prevent spontaneous bleeding. In addition to factor replacement, desmopressin may be used for Hemophilia A to stimulate the release of stored clotting factors. Antifibrinolytics, such as tranexamic acid, help prevent bleeding. Patients may also undergo physical therapy to manage joint health and improve mobility, alongside genetic counselling for family planning.
The coagulation factor deficiency epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for coagulation factor deficiency by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for coagulation factor deficiency and their trends. The data is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.
The coagulation factor deficiency epidemiology data and findings for the United States, EU-4 (Germany, Spain, Italy, France), the United Kingdom, Japan, and India are also provided in the epidemiology section.
In the United States, approximately 33,000 males are living with hemophilia, with a prevalence of 1 in 125,000 males globally. Hemophilia A is the most common, affecting 1 in 5000 males, while Hemophilia B has a prevalence of 3.8 per 100,000 live males. In infants, Vitamin K Deficiency Bleeding (VKDB) is more common before they start regular foods, with late VKDB occurring in 1 in 14,000 to 1 in 25,000 infants. Babies not receiving a vitamin K shot at birth are 81 times more likely to develop late VKDB.
Country Specific Stats:
Country |
Prevalence (Unit) |
United States |
1 in 125,000 males |
United Kingdom |
XX |
Germany |
XX |
Italy |
XX |
France |
XX |
Spain |
XX |
Japan |
XX |
India |
XX |
*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*
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Report Features |
Details |
Base Year |
2024 |
Historical Period |
2018-2024 |
Forecast Period |
2025-2034 |
Epidemiology Statistics Provided |
|
Segmentation Provided |
|
Geographies Covered |
|
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United States
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+1-415-325-5166
Vietnam
193/26/4 St.no.6, Ward Binh Hung Hoa, Binh Tan District, Ho Chi Minh City
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United States (Head Office)
30 North Gould Street, Sheridan, WY 82801
+1-415-325-5166
Australia
63 Fiona Drive, Tamworth, NSW
+61-448-061-727
India
C130 Sector 2 Noida, Uttar Pradesh 201301
+91-858-608-1494
Philippines
40th Floor, PBCom Tower, 6795 Ayala Avenue Cor V.A Rufino St. Makati City, 1226.
+63-287-899-028, +63-967-048-3306
United Kingdom
6 Gardner Place, Becketts Close, Feltham TW14 0BX, Greater London
+44-753-713-2163
Vietnam
193/26/4 St.no.6, Ward Binh Hung Hoa, Binh Tan District, Ho Chi Minh City
+84-865-399-124
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