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Report Overview

Synovial sarcoma accounts for nearly 10% of all soft tissue tumors. With 800-1000 individuals undergoing a diagnosis for the condition each year, it has an incidence rate of 0.177 per 100,000  people in the United States. As a result, several healthcare and pharmaceutical companies are involved in developing effective synovial sarcoma therapeutics to treat and manage the disease efficiently.

  • Major companies involved in the synovial sarcoma treatment market include Adaptimmune, Eli Lilly and Company, and Takara Bio Inc., among others.
  • Leading drugs currently under the drug pipeline include Ramucirumab, FHD-609, and CFT8634.
  • With regulatory authorities like the United States FDA and EMA offering breakthrough designations and fast-track approvals to various drugs, the synovial sarcoma pipeline landscape is expected to witness substantial growth in coming years.

Report Coverage

The Synovial Sarcoma Drug Pipeline Report by Expert Market Research gives comprehensive insights into synovial sarcoma therapeutic drugs currently undergoing clinical trials for synovial sarcoma treatment. It covers various aspects related to the details of each of these drugs under development. The synovial sarcoma report assessment includes an analysis of over 100 pipeline drugs and 50+ companies. It will include an analysis based on efficacy and safety measure outcomes published for the trials including their adverse effects on synovial sarcoma.

The detailed analysis of each drug, drug class, clinical studies, phase type, drug type, route of administration and ongoing synovial sarcoma pipeline development activities are covered in the report.

Synovial Sarcoma Drug Pipeline Outlook

Synovial sarcoma is a rare cancer that primarily affects muscles or ligaments, including arms, legs, knees or feet. The symptoms for this condition may vary based on tumor location or form. It is commonly diagnosed through X-ray, CT scan, ultrasound, or biopsy.

In August 2024, the United States FDA approved Adaptimmune's Tecelra (afamitresgene autoleucel) for treating unresectable or metastatic synovial sarcoma. It is a gene therapy for adults who have received prior chemotherapy. The approval was granted on the basis of an open-label clinical trial that involved 44 patients. The overall response rate (ORR) was 43.2%. With synovial sarcoma emerging drugs belonging to various drug classes getting approvals from vital regulatory authorities, the drug pipeline for synovial sarcoma is promising.

Synovial Sarcoma – Drug Pipeline Therapeutic Assessment

This section of the report covers the analysis of synovial sarcoma drug candidates based on various segmentations such as:

By Phase

EMR’s pipeline assessment report covers 50+ drug analyses based on phase.

  • Late-Stage Products (Phase 3 and Phase 4)
  • Mid-Stage Products (Phase 2)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products

By Drug Class

EMR’s synovial sarcoma therapeutic assessment report covers 50+ drug analyses based on drug classes:

  • Chemotherapy Agent
  • Targeted Therapy
  • Immunotherapy

By Route of Administration

EMR’s synovial sarcoma clinical assessment covers 50+ drug analyses based on the route of administration.

  • Oral
  • Parenteral
  • Others

Synovial Sarcoma – Pipeline Assessment Segmentation, By Phases

The synovial sarcoma report insight covers phase I, phase II, phase III, phase IV, and early phase drugs. The coverage includes an in-depth analysis of each drug across these phases. According to EMR analysis, phase II covers a major share of the total clinical trials conducted, with over 60 drugs in the pipeline.

Synovial Sarcoma – Pipeline Assessment Segmentation, By Drug Class

The drug class categories covered under synovial sarcoma pipeline analysis include chemotherapy agents, targeted therapies and immunotherapies, among others. Immunotherapy can be further categorised into immune checkpoint inhibitors as well as T-cell therapies. Each drug class has a different mode of action, and it is recommended based on disease prognosis. Chemotherapy drugs work by killing tumor cells while targeted therapy drugs interfere with particular molecular targets and inhibit further cell growth.

The synovial sarcoma report provides a comparative analysis of the drug classes for each drug in various phases of clinical trials.

Synovial Sarcoma Clinical Trials Assessment – Competitive Dynamics

The EMR report for the synovial sarcoma drug pipeline covers the profile of key companies involved in clinical trials and their drugs under development. Below is the list of a few players involved in synovial sarcoma pipeline landscape:

Synovial Sarcoma – Emerging Drugs Profile

Ramucirumab (LY3009806)

Sponsored by Eli Lilly and Company, ramucirumab (in combination with chemotherapy) is being investigated to treat recurrent, refractory, or relapsed pediatric synovial sarcoma. As a part of the CAMPFIRE master protocol, the synovial-sarcoma drug candidate is being evaluated in a randomized open-label Phase 1/2 study.

FHD-609

The drug is under evaluation for treating advanced synovial sarcoma or advanced SMARCB1-loss tumors....

CFT8634

As a part of an open-label non-randomized, first-in-human Phase 1/2 study, this synovial-sarcoma the...

Radiolabeled OTSA101-DTPA

Developed by OncoTherapy Science, Inc., this anti-frizzled homolog 10 monoclonal antibody, is being ...

*Please note that this is only a partial list; the complete list of key players is available in the full report. Additionally, the list of key players can be customized to better suit your needs.*

Reasons To Buy This Report

The Synovial Sarcoma Drug Pipeline Analysis Report provides a strategic overview of the latest and future landscape of treatments for synovial sarcoma. It provides necessary information for making informed investment decisions along with research, development, and strategic planning efforts. The stakeholders will benefit from the essential insights into synovial sarcoma collaborations, market trends, regulatory environments, and potential growth opportunities.

Key Questions Answered in the Synovial Sarcoma – Pipeline Assessment Report

  • What is the current landscape of synovial sarcoma pipeline drugs?
  • Which companies/institutions are developing synovial sarcoma emerging drugs?
  • How many phase II drugs are currently present in synovial sarcoma pipeline drugs?
  • Which company is leading the synovial sarcoma pipeline development activities?
  • What is the current synovial sarcoma therapeutic assessment?
  • What are the opportunities and challenges present in the synovial sarcoma drug pipeline landscape?
  • What is the efficacy and safety profile of synovial sarcoma pipeline drugs?
  • Which companies/institutions are involved in synovial sarcoma collaborations aimed at providing enhanced therapeutic alternatives for patients?
  • What are the geographies covered for clinical trials in synovial sarcoma?

Related Reports

Synovial Sarcoma Market

Clinical Trials Market

Pharmaceuticals Market

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Scope of the Report Details
Drug Pipeline by Clinical Trial Phase
  • Late-Stage Products (Phase III and Phase IV)
  • Mid-Stage Products (Phase II)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products 
Route of Administration
  • Oral
  • Parenteral
  • Others
Drug Classes
  • Chemotherapy Agent
  • Targeted Therapy
  • Immunotherapy
Leading Sponsors Covered
  • Adaptimmune
  • Eli Lilly and Company
  • Takara Bio Inc.
  • Foghorn Therapeutics Inc.
  • C4 Therapeutics, Inc.
  • OncoTherapy Science, Inc.
Geographies Covered    
  • North America
  • Europe
  • Asia Pacific
  • Others

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