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Report Overview

Spinal fusion is a surgical procedure used to permanently connect two or more vertebrae in the spine, eliminating motion between them to relieve pain or correct deformities. According to Yubao Lu et al. (2024), the incidence of spinal cord injury (SCI) varies widely, ranging from 7 to 152.2 cases per million people. As per the Spinal Fusion Drug Pipeline Analysis by Expert Market Research, the market is witnessing significant advancements driven by the development of biologics, bone graft substitutes, and minimally invasive fusion therapies. Increasing prevalence of degenerative spinal disorders and rising R&D investments are expected to accelerate pipeline growth in the coming years.

Key Take aways

  • Major companies involved in the spinal fusion pipeline analysis include Kuros BioSciences B.V., Zimmer Biomet, and others.
  • Leading drugs currently in the pipeline include Pregabalin, Ketorolac, and others.

Report Coverage

The Spinal Fusion Pipeline Report by Expert Market Research gives comprehensive insights into ongoing spinal fusion clinical trials. It covers various aspects related to the details of spinal fusion drugs under development. The report includes the analysis of over 100 pipeline drugs and 50+ companies. The spinal fusion pipeline landscape will include an analysis based on efficacy and safety measure outcomes published for the trials including their adverse effects on patients suffering from spinal fusion.

The detailed analysis of each drug, drug class, clinical studies, phase type, drug type, route of administration and ongoing spinal fusion pipeline development activities are covered. Moreover, spinal fusion collaborations and commercial assessments are offered, helping stakeholders to make informed decisions.

Spinal Fusion Pipeline Analysis By Drug Class

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Spinal Fusion Drug Pipeline Outlook

Spinal fusion involves the process of joining two or more spinal bones. The connection prevents movement and inhibits pain. During a spinal infusion surgery, a healthcare provider may use bonelike material, metal plates, screws or rods to hold bones together. This allows the bone to fuse and recover. Spinal fusion can help with the symptoms of degenerative disk disease, spinal stenosis, scoliosis, spondylolisthesis and tumor among others.

The spinal fusion treatment landscape involves the use of drugs and medications, that are often used to manage pain, and inflammation associated with the condition. In addition, bone growth stimulators and vitamin D supplements are also used to support bone health and expedite healing. Healthcare providers follow a multidisciplinary approach to optimize patient recovery and ensure procedure success. Currently, oxycodone and methocarbamol are commonly used in spinal fusion procedures. While oxycodone is an analgesic, methocarbamol is a skeletal muscle relaxant often prescribed post-operatively. Researchers are working on developing various drugs that help in manage the condition with higher efficacy.

Spinal Fusion – Drug Pipeline Therapeutic Assessment

This section of the report covers the analysis of spinal fusion drug candidates based on several segmentations including:

By Phase

EMR’s pipeline assessment report covers 50+ drug analyses based on phase:

  • Late-Stage Products (Phase 3 and Phase 4)
  • Mid-Stage Products (Phase 2)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products

By Drug Class

EMR’s spinal fusion therapeutic assessment report covers 50+ drug analyses based on drug classes:

  • Analgesics
  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
  • Muscle Relaxants
  • Neuropathic Pain Medications
  • Bone Growth Stimulating Agents
  • Corticosteroids
  • Antibiotics

By Route of Administration

EMR’s pipeline assessment report covers 50+ drug analyses based on the route of administration:

  • Oral
  • Parenteral
  • Others

Spinal Fusion – Pipeline Assessment Segmentation, By Phases

The report covers phase I, phase II, phase III, phase IV, and early phase drugs. The coverage includes an in-depth analysis of each drug across these phases. According to EMR analysis, phase IV covers a major share of the total spinal fusion clinical trials. There are around 65 drugs in phase IV of spinal fusion drugs.

Spinal Fusion – Pipeline Assessment Segmentation, By Drug Classes

The drug molecules categories covered under spinal fusion pipeline analysis include analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs), muscle relaxants, neuropathic pain medications, bone growth stimulating agents, corticosteroids, and antibiotics. Each drug class has a specific function and is administered based on patient specifications.

Spinal Fusion Clinical Trials Therapeutic Assessment – Competitive Dynamics

The EMR spinal fusion drug report insights involve the profile of key companies involved in clinical trials and their drugs under development. Below is the list of a few players involved in spinal fusion clinical trials:

  • Kuros BioSciences B.V.
  • Zimmer Biomet
  • Novo Nordisk A/S
  • Pacira Pharmaceuticals, Inc.
  • Exela Pharma Sciences, LLC.

Spinal Fusion – Emerging Drugs Profile

This section covers the detailed analysis of each drug under multiple phases including phase I, phase II, phase III, phase IV, and emerging drugs for spinal fusion. It includes product description, trial ID, study type, drug class, mode of administration, and recruitment status of spinal fusion drug candidates.

Pregabalin

This is a neuropathic pain drug that is being tested to treat multi-modal pain regimen post-spinal surgery. Sponsored by the Hospital for Special Surgery, New York, the drug is currently in phase IV clinical trials.

Ketorolac

Sponsored by the Ascension South East Michigan, this spinal fusion drug candidate is a low-dose ketorolac under investigation as an analgesic during the early post-operative period (within 48 hours) of spinal fusion.

Tranexamic Acid

Tranexamic acid is being evaluated as an alternative to reduce bleeding in individuals undergoing spinal fusion surgery. Sponsored by Exela Pharma Sciences, LLC, it is in Phase 3 of a multicenter, randomized, double-blind, parallel-group study.

*Please note that this is only a partial list; the complete list of drugs will be available in the full report.*

Reasons To Buy This Report

The Spinal Fusion Drug Pipeline Insight Report provides a strategic overview of the latest and future landscape of treatments for spinal fusion. It provides necessary information for making informed investment decisions along with research, development, and strategic planning efforts. The stakeholders will benefit from the essential insights into spinal fusion collaborations, regulatory environments, and potential growth opportunities within the treatment landscape.

Key Questions Answered in the Spinal Fusion – Pipeline Insight Report

  • Which companies/institutions are leading the spinal fusion drug development?
  • What is the efficacy and safety profile of spinal fusion pipeline drugs?
  • Which company is leading the spinal fusion pipeline development activities?
  • What is the current spinal fusion commercial assessment?
  • What are the opportunities and challenges present in the spinal fusion drug pipeline landscape?
  • What is the efficacy and safety profile of spinal fusion pipeline drugs?
  • Which company is conducting major trials for spinal fusion drugs?
  • Which companies/institutions are involved in spinal fusion collaborations aimed at providing enhanced therapeutic alternatives for patients?
  • What are the geographies covered for clinical trials in spinal fusion?

Related Reports

Spinal Fusion Devices Market

Spinal Cord Injury Market

Spinal Implants and Surgery Devices

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Scope of the Report Details
Drug Pipeline by Clinical Trial Phase
  • Late-Stage Products (Phase III and Phase IV)
  • Mid-Stage Products (Phase II)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products
Route of Administration
  • Oral
  • Parenteral
  • Others
Drug Classes
  • Analgesics 
  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
  • Muscle Relaxants
  • Neuropathic Pain Medications
  • Bone Growth Stimulating Agents
  • Corticosteroids
  • Antibiotics
Leading Sponsors Covered
  • Kuros BioSciences B.V.
  • Zimmer Biomet
  • Novo Nordisk A/S
  • Pacira Pharmaceuticals, Inc.
  • Exela Pharma Sciences, LLC.
Geographies Covered
  • North America
  • Europe
  • Asia Pacific
  • Others

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