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Report Overview

Non-small cell lung cancer (NSCLC) accounts for 85% of all lung cancer types. As per cancer.gov calculations, in 2024, around 234,580 new cases are likely to occur in the United States population. Moreover, 125,070 deaths are predicted in 2024. Hence, leading healthcare companies like AstraZeneca, Merck and Daiichi Sankyo along with research institutions are meticulously working to develop effective drugs for the treatment of the condition. This has led to a significant number of drugs currently in the development pipeline.

  • Major companies involved in the non-small cell lung cancer (NSCLC) emerging drugs market include AstraZeneca, Daiichi Sankyo Co., Ltd., GlaxoSmithKline, Bayer AG, Hoffmann-La Roche, Pfizer, Inc., and Merck KGaA, among others.
  • Leading drugs currently under the drug pipeline include Sasanlimab, HER3-DXd and Osimertinib, among others.
  • Regulatory authorities like the United States FDA and EMA play a critical role in the non-small cell lung cancer (NSCLC) treatment as they provide fast-track approvals and breakthrough designations to expedite access to new and effective treatments.

Report Coverage

The Non-Small Cell Lung Cancer (NSCLC) Drug Pipeline Insight Report by Expert Market Research gives comprehensive insights into non-small cell lung cancer therapeutics currently undergoing clinical trials. It covers various aspects related to the details of each of these drugs under development for non-small cell lung cancer. The non-small cell lung cancer report assessment includes the analysis of over 100 pipeline drugs and 50+ companies. The non-small cell lung cancer pipeline landscape will include an analysis based on efficacy and safety measure outcomes published for the trials including their adverse effects on patients suffering from the condition, and alignment with non-small cell lung cancer treatment guidelines to ensure optimal care practices.

The assessment part will include a detailed analysis of each drug, drug class, clinical studies, phase type, drug type, route of administration, and ongoing product development activities related to non-small cell lung cancer. Moreover, non-small cell lung cancer (NSCLC) collaborations and commercial assessments are offered, helping stakeholders to make informed decisions.

Non-Small Cell Lung Cancer (NSCLC) Drug Pipeline Outlook

Non-small cell lung cancer (NSCLC)  is the most commonly occurring lung cancer type and can be further categorized into squamous cell carcinoma, large cell carcinoma, and adenocarcinoma. A variety of drugs are used in non-small cell lung cancer (NSCLC) treatment, depending on the stage of the cancer, specific genetic mutations, and the overall health of the patient. These drugs can be categorized into several main classes such as chemotherapy, targeted therapy, and immunotherapy, among others. Chemotherapy includes platinum-based drugs, and antimetabolites while targeted therapy constitutes EGFR inhibitors, ALK inhibitors and ROS1 inhibitors. PD-1 and PD-L1 inhibitors are also common drug classes within immunotherapy drugs.

Common symptoms of non-small cell lung cancer (NSCLC) include persistent cough, chest pain, shortness of breath and fatigue. Smoking is one of the leading causes of the condition. Therefore, the increasing prevalence of smoking in the global population fuels the non-small cell lung cancer (NSCLC) market growth.  

The non-small cell lung cancer (NSCLC) pipeline report covers the pathophysiology and epidemiology, developing treatment, and the progress and future aspects of ongoing clinical trials in detail.

Non-Small Cell Lung Cancer (NSCLC) Cancer – Drug Pipeline Therapeutic Assessment

This section of the report covers the analysis of non-small cell lung cancer (NSCLC) drugs based on various segmentations such as:

By Phase

EMR’s non-small cell lung cancer (NSCLC) cancer therapeutic assessment report covers 50+ drug analysis based on phase.

  • Late-Stage Products (Phase 3 and Phase 4)
  • Mid-Stage Products (Phase 2)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products

By Route of Administration

EMR’s pipeline assessment report covers 50+ drug analysis based on the route of administration.

  • Oral
  • Parenteral
  • Others

Non-Small Cell Lung Cancer (NSCLC) – Pipeline Assessment Segmentation, By Phases

The report covers phase I, phase II, phase III, phase IV, and early phase drugs. The coverage includes in depth analysis of each drug across these phases. According to EMR analysis, phase II trials cover a major share of the total non-small cell lung cancer (NSCLC) clinical trials conducted, with approximately 3,000 plus drugs in the pipeline.  

Non-Small Cell Lung Cancer (NSCLC)– Pipeline Assessment Segmentation, By Route of Administration

The route of administration categories covered under the non-small cell lung cancer (NSCLC) pipeline landscape include oral, parenteral, and others. The report provides a comparative analysis of the route of administration for each drug in various phases of clinical trials. According to EMR analysis, the parenteral route holds a significant market share based on the route of administration. 

Non-Small Cell Lung Cancer (NSCLC) Clinical Trials Assessment – Competitive Dynamics

The EMR non-small cell lung cancer (NSCLC) drug pipeline report insights cover the profile of key companies involved in clinical trials and their drugs under development. Below is the list of a few players involved in pancreatic cancer clinical trials:

  • AstraZeneca
  • Daiichi Sankyo Co., Ltd.
  • GlaxoSmithKline
  • Bayer AG
  • Hoffmann-La Roche
  • Novartis Pharmaceuticals
  • Seagen Inc.
  • Pfizer, Inc.
  • Merck KGaA
  • Others

Non-Small Cell Lung Cancer (NSCLC) – Emerging Drugs Profile

This section covers the detailed analysis of each drug under multiple phases including phase I, phase II, phase III, phase IV, and emerging drugs. It covers include product description, trial ID, study type, drug class, mode of administration, and recruitment status of non-small cell lung cancer (NSCLC) drug candidates.

Sasanlimab – Pfizer

Sasanlimab is a PD-1 antagonist monoclonal antibody, designed to be used in combination with a different targeted therapy in each set of the study. Sponsored by Pfizer, Sasanlimab is part of Landscape 1011 clinical research study for individuals with stage 3b or 4 NSCLC. Phase 1b of the sub-study will emphasize on analyzing the safety while phase 2 will focus on evaluating anti-tumor activity in combination.

HER3-DXd – Daiichi Sankyo

Designed to treat metastatic or unresectable non-small cell lung cancer (NSCLC), Daiichi Sankyo’s HER3-DXd is being evaluated for its efficacy and antitumor activity. The Open-Label phase 1 study is divided into two parts, including dose expansion and dose escalation. It will be assessed on individuals with advanced NSCLC, having KRAS-G12C mutation.

Osimertinib – AstraZeneca

This interventional study by AstraZeneca evaluates neoadjuvant osimertinib as monotherapy or in combination with chemotherapy, versus standard of care chemotherapy alone. Currently, under phase III, it is investigating the treatment in patients with resectable EGFRm non-small cell lung cancer.

Pembrolizumab (MK-3475) – Merck

As a part of KEYMAKER-U01 Substudy 1, a phase 2 umbrella study sponsored by Merck Sharp & Dohme LLC, pembrolizumab (MK-3475) PLUS chemotherapy in combination with vibostolimab (MK-7684), boserolimab (MK-5890), MK-4830, or MK-0482 is being evaluated for treating advanced non-small cell lung cancer.

*Please note that this is only a partial list; the complete list of drugs will be available in the full report.*

Reasons To Buy This Report

The Non-Small Cell Lung Cancer (NSCLC) Drug Pipeline Analysis Report provides a strategic overview of the latest and future landscape of treatments for non-small cell lung cancer (NSCLC). It provides necessary information for making informed investment decisions along with research, development, and strategic planning efforts. The stakeholders will benefit from the essential insights into non-small cell lung cancer (NSCLC) collaborations, regulatory environments, and potential growth opportunities within the treatment landscape.

Key Questions Answered in the Non-Small Cell Lung Cancer (NSCLC) – Pipeline Assessment Report

  • Which companies/institutions are leading the non-small cell lung cancer (NSCLC) drug development?
  • What is the efficacy and safety profile of non-small cell lung cancer (NSCLC) pipeline drugs?
  • Which company is leading the non-small cell lung cancer (NSCLC) pipeline development activities?
  • What is the current non-small cell lung cancer (NSCLC) commercial assessment?
  • What are the opportunities and challenges present in the non-small cell lung cancer (NSCLC) drug pipeline landscape?
  • What is the efficacy and safety profile of non-small cell lung cancer (NSCLC) pipeline drugs?
  • Which company is conducting major trials for non-small cell lung cancer (NSCLC) drugs?
  • Which companies/institutions are involved in non-small cell lung cancer (NSCLC) collaborations aimed at providing enhanced therapeutic alternatives for patients?
  • What are the geographies covered for clinical trials in non-small cell lung cancer (NSCLC)?

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*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

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Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Scope of the Report Details
Drug Pipeline by Clinical Trial Phase
  • Late-Stage Products (Phase III and Phase IV)
  • Mid-Stage Products (Phase II)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products 
Route of Administration
  • Oral
  • Parenteral
  • Others
Drug Classes
  • Small Molecule
  • Polymer
  • Monoclonal Antibody
  • Peptides
  • Gene Therapy
Treatment Type
  • Chemotherapy
  • Immunotherapy
  • Hormone Therapy
  • Targeted Therapy
  • Others
Leading Sponsors Covered
  • AstraZeneca
  • Daiichi Sankyo Co., Ltd.
  • GlaxoSmithKline
  • Bayer AG
  • Hoffmann-La Roche
  • Novartis Pharmaceuticals
  • Seagen Inc.
  • Pfizer, Inc.
  • Merck KGaA
  • Others
Geographies Covered
  • North America
  • Europe
  • Asia Pacific
  • Others

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