Constipation Drug Pipeline Analysis Report 2025

Report Coverage

The Constipation Drug Pipeline Insight Report by Expert Market Research gives comprehensive insights into constipation therapeutics currently undergoing clinical trials. It covers various aspects related to the details of each of these drugs under development for constipation. The constipation report assessment includes the analysis of over 100 pipeline drugs and 50+ companies. The constipation pipeline landscape will include an analysis based on efficacy and safety measure outcomes published for the trials, including their adverse effects on patients suffering from the condition, and alignment with constipation treatment guidelines to ensure optimal care practices.

The assessment part will include a detailed analysis of each drug, drug class, clinical studies, phase type, drug type, route of administration, and ongoing product development activities related to constipation.

Constipation Drug Pipeline Outlook

Constipation is a common digestive condition characterized by infrequent, difficult, or painful bowel movements. It occurs when the colon absorbs too much water from waste, leading to dry, hard stools. Factors such as a low-fiber diet, dehydration, lack of physical activity, and certain medications can contribute to constipation.

Constipation treatments include lifestyle changes like increasing fiber intake, hydration, and physical activity. Over-the-counter laxatives, stool softeners, and prescription medications targeting gut motility are also effective. Advanced treatments include prokinetic agents and novel therapeutic drugs, offering improved relief for chronic cases and enhancing patient outcomes.

Constipation Epidemiology

Constipation is a widespread gastrointestinal issue with varying prevalence across regions. In North America, approximately 16% of the population is affected, with higher rates in women and the elderly. The United Kingdom reports prevalence between 4% and 20%, leading to significant hospital admissions. In Germany, 6.8% of children experience constipation while in India, the prevalence ranges from 16.8% to 24.8%, highlighting the growing need for advanced constipation therapeutic products.

Constipation – Drug Pipeline Therapeutic Assessment

Constipation – Pipeline Assessment Segmentation, By Phases

The report covers phase I, phase II, phase III, phase IV, and early-phase drugs. The coverage includes an in-depth analysis of each drug across these phases. According to EMR analysis, phase II covers a major share of the total constipation clinical trials.

Constipation – Pipeline Assessment Segmentation, By Drug Classes

The drug molecule categories covered under the constipation pipeline analysis include small molecules, biologics, peptides, probiotics therapies, gene therapies. The constipation report provides a comparative analysis of the drug classes for each drug in various phases of clinical trials for constipation.

Constipation Clinical Trials Therapeutic Assessment – Competitive Dynamics

The EMR report for the constipation drug pipeline covers the profile of key companies involved in clinical trials and their drugs under development. It provides a detailed constipation therapeutic assessment, analyzing the competitive dynamics of the clinical trial landscape. Below is the list of a few players involved in constipation clinical trials:

• AbbVie
• Ardelyx
• BioGaia Pharma AB
• HK inno.N Corporation
• Shionogi
• Ironwood Pharmaceuticals, Inc.
• Braintree Laboratories
• Xian-Janssen Pharmaceutical Ltd.

Constipation Emerging Drugs Profile

This section covers the detailed analysis of each drug under multiple phases, including phase I, phase II, phase III, phase IV, and emerging drugs for constipation. It includes product description, trial ID, study type, drug class, mode of administration, and recruitment status of constipation drug candidates.

Drug: Linaclotide

Linaclotide, sponsored by AbbVie, is currently being evaluated in a Phase III trial for pediatric patients aged 2 to 5 years with functional constipation (FC). This study aims to assess adverse events and symptom changes. Linaclotide is a guanylate cyclase-C (GC-C) agonist that increases intestinal fluid secretion, accelerates transit, and may reduce pain-sensing nerve activity in the intestine.

Drug: Naldemedine

Naldemedine, developed by Shionogi & Co., Ltd., is being tested in a Phase I/II trial to asse...

*Please note that this is only a partial list; the complete list of drugs will be available in the full report.*

Reasons To Buy This Report

The Constipation Drug Pipeline Insight Report provides a strategic overview of the latest and future landscape of treatments for constipation. It provides necessary information for making informed investment decisions along with research, development, and strategic planning efforts. The stakeholders will benefit from the essential insights into constipation collaborations, regulatory environments, and potential growth opportunities.

Key Questions Answered in the Constipation – Pipeline Insight Report

• Which companies/institutions are leading the constipation drug development?
• What is the efficacy and safety profile of constipation pipeline drugs?
• Which company is leading the constipation pipeline development activities?
• What is the current constipation commercial assessment?
• What are the opportunities and challenges present in the constipation drug pipeline landscape?
• What is the efficacy and safety profile of constipation pipeline drugs?
• Which company is conducting major trials for constipation drugs?
• Which companies/institutions are involved in constipation collaborations aimed at providing enhanced therapeutic alternatives for patients?
• What are the geographies covered for clinical trials in constipation?

Related Reports

Constipation Treatment Market Report and Forecast

Chronic Idiopathic Constipation (CIC) Epidemiology Forecast

Global Opioid Induced Constipation Market Report and Forecast

Global Clinical Trials Market