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Report Overview

As per the estimates from CDC's (Centers for Disease Control and Prevention) Autism and Developmental Disabilities Monitoring (ADDM) Network, around 1 in 36 children were reported to be identified with autism spectrum disorder. With the growing number of cases, there is a heightened focus on expediting the development of promising autism drugs and accelerating clinical trials. Moreover, rising public awareness and advocacy from autism organizations are also fuelling the demand for advanced treatment options.

  • Major companies involved in the autism pipeline drugs market include Curemark, Astrogen, Inc., and ACADIA Pharmaceuticals Inc., among others.
  • Leading drugs currently under the pipeline include CM-AT and AST-001, among others.
  • The increasing prevalence of autism along with the rising advancements in neurological and genetic research are poised to positively influence the autism pipeline landscape.

Report Coverage

The Autism Drug Pipeline Insight Report by Expert Market Research gives comprehensive insights into autism therapeutics currently undergoing clinical trials. It covers various aspects related to the details of each of these drugs under development for Autism. The autism report assessment includes the analysis of over 100 pipeline drugs and 50+ companies. The autism pipeline landscape will include an analysis based on efficacy and safety measure outcomes published for the trials including their adverse effects on patients suffering from the condition, and alignment with autism treatment guidelines to ensure optimal care practices.

The assessment part will include a detailed analysis of each drug, drug class, clinical studies, phase type, drug type, route of administration, and ongoing product development activities related to autism.

Autism Drug Pipeline Outlook

Autism or autism spectrum disorder (ASD) refers to a neurological and developmental disorder characterized by deficits in social communication and social interaction. Autistic individuals typically show inflexible, repetitive, and restricted patterns of interests, behaviors, and activities. Some people with autism can live independently whereas certain individuals may require life-long support and care.

Behavioral therapy is a widely used approach to improve social, communication, and learning skills in autistic people. For irritability and aggression, autism therapeutics include FDA-approved risperidone and aripiprazole for managing severe behavioral symptoms. Pharmaceutical companies are actively developing novel drug candidates such as gene and RNA-based therapies, cannabidiol (CBD), and oxytocin therapies. Additionally, the adoption of innovative technologies in drug development, along with adherence to autism treatment guidelines, is expected to improve patient outcomes and aid pipeline expansion in the near future.

Autism Epidemiology

According to the World Health Organisation (WHO), approximately 1 in 100 children are affected by autism, with the prevalence of the condition unknown in many low- and middle-income countries. On the other hand, the CDC's Autism and Developmental Disabilities Monitoring (ADDM) Network estimates that 1 in 36 children has been identified with autism.

Autism spectrum disorder is roughly 4 times more common in boys than in girls. It is reported to occur in all ethnic, racial, and socioeconomic groups.

Autism – Drug Pipeline Therapeutic Assessment

This section of the report covers the analysis of autism drug candidates based on several segmentations including:

By Phase

  • Late-Stage Products (Phase 3 and Phase 4)
  • Mid-Stage Products (Phase 2)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products

By Drug Class

  • Small Molecules
  • Biologics
  • Peptides
  • Gene and RNA-based Therapies
  • Natural Compounds and Cannabinoids

By Route of Administration

  • Oral
  • Parenteral
  • Others

Autism – Pipeline Assessment Segmentation, By Phases

The report covers phase I, phase II, phase III, phase IV, and early phase drugs. The coverage includes an in-depth analysis of each drug across these phases. According to EMR analysis, phase II covers a major share of the total clinical trials, with a substantial number of autism emerging drugs undergoing clinical development.

Autism – Pipeline Assessment Segmentation, By Drug Classes

The drug molecule categories covered under autism pipeline analysis include small molecules, biologics, peptides, gene and RNA-based therapies, and natural compounds and cannabinoids. The autism report provides a comparative analysis of the drug classes for each drug in various phases of clinical trials for autism.

Autism Clinical Trials Therapeutic Assessment – Competitive Dynamics

The EMR report for the autism drug pipeline covers the profile of key companies involved in clinical trials and their drugs under development. It provides a detailed autism therapeutic assessment, analyzing the competitive dynamics of the clinical trial landscape. Below is the list of a few players involved in autism clinical trials:

  • Curemark
  • Aardvark Therapeutics, Inc.
  • MapLight Therapeutics
  • Intra-Cellular Therapies, Inc.
  • Astrogen, Inc.
  • ACADIA Pharmaceuticals Inc.
  • AbbVie

Autism – Emerging Drugs Profile

Major drugs currently in the drug pipeline are as follows:

Drug: AST-001

Sponsored by Astrogen, Inc., the objective of this randomized, double-blinded, multicenter clinical trial is to investigate the efficacy and safety of AST-001 in children with autism spectrum disorder. The study is under Phase III clinical development and has an estimated 160 participants.

Drug: CM-AT

Curemark is conducting a Phase III open-label extension study aimed at examining the efficacy and safety of autism drug candidate CM-AT in treating autism with all levels of fecal chymotrypsin. The interventional study has enrolled about 405 children and is expected to be completed by January 2025.

*Please note that this is only a partial list; the complete list of drugs will be available in the full report.*

Reasons To Buy This Report

The Autism Drug Report provides a strategic overview of the latest and future landscape of treatments for autism. It provides necessary information for making informed investment decisions along with research, development, and strategic planning efforts. The stakeholders will benefit from the essential insights into market trends, regulatory environments, and potential growth opportunities within autism pipeline insights.

Key Questions Answered in the Autism – Pipeline Insight Report

  • What is the current landscape of autism pipeline drugs?
  • Which companies/institutions are developing autism therapeutic drugs?
  • How many phase II drugs are currently present in autism pipeline drugs?
  • Which company is leading the autism pipeline development activities?
  • What is the current autism commercial assessment?
  • What are the opportunities and challenges present in the autism drug pipeline landscape?
  • What is the efficacy and safety profile of autism pipeline drugs?
  • Which companies/institutions are involved in autism collaborations aimed at providing enhanced therapeutic alternatives for patients?
  • What are the geographies covered for clinical trials in autism?

Related Reports

Autism Spectrum Disorders Market

Autism Spectrum Disorder Therapeutics Market

Global Clinical Trials Market

*While we strive to always give you current and accurate information, the numbers depicted on the website are indicative and may differ from the actual numbers in the main report. At Expert Market Research, we aim to bring you the latest insights and trends in the market. Using our analyses and forecasts, stakeholders can understand the market dynamics, navigate challenges, and capitalize on opportunities to make data-driven strategic decisions.*

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Report Summary

Explore our key highlights of the report and gain a concise overview of key findings, trends, and actionable insights that will empower your strategic decisions.

Key Highlights of the Report

Please note that the figures mentioned in the description serve as estimates and may vary from the actual figures presented in the final report.

Scope of the Report

Details

Drug Pipeline by Clinical Trial Phase

  • Late-Stage Products (Phase III and Phase IV)
  • Mid-Stage Products (Phase II)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products

Route of Administration

  • Oral
  • Parenteral
  • Others

Drug Classes

  • Small Molecules
  • Biologics
  • Peptides
  • Gene and RNA-based Therapies
  • Natural Compounds and Cannabinoids

Leading Sponsors Covered

  • Curemark
  • Aardvark Therapeutics, Inc.
  • MapLight Therapeutics
  • Intra-Cellular Therapies, Inc.
  • Astrogen, Inc.
  • ACADIA Pharmaceuticals Inc.
  • AbbVie

Geographies Covered

  • North America
  • Europe
  • Asia Pacific
  • Others

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